重度子痫前期107例临床分析  

Clinical Analysis of 107 Cases with Severe Preeclampsia

作　　者：吴婕[1] 肖虹[1] 朱蓓[1] 

机构地区：[1]昆明医学院第一附属医院妇产科,云南昆明650032

出　　处：《昆明医学院学报》2008年第5期149-151,155,共4页Journal of Kunming Medical College

摘　　要：目的分析重度子痫前期的临床特点,终止妊娠时机对围生儿的影响,进一步提高对该疾病的认识和处理能力.方法回顾性分析本院107例重度子痫前期的临床资料.结果重度子痫前期的发病率为1.2%,围生儿结局与发病时间及终止妊娠的周数有关.34周前终止者重度窒息、围生儿死亡率显著增加(P<0.01),轻度窒息仅34～37周和37周以上有差异(P<0.05);胎儿宫内生长受限(FGR)37周以下较37周以上有差异(P<0.05).重度子痫前期的早产发生率57%,围生儿死亡率8.9%.结论重度子痫前期易导致母亲及围生儿预后不良,选择适当时机终止妊娠可降低母婴并发症,保证母亲安全.Objective To analyze clinical feature of severe preeclampsia and the effect on the perinatal outcome to improve the diagnosis and treatment. Methods We analyzed retrospectively 107 pregnancies with severe preeclampsia from October 2003 to October 2007. Results Incidence of severe preeclampsia was 1.2%. Perinatal outcome was associated with the gestational weeks at onset of severe preeclampsia. The rate of severe neonatal asphyxia and perinatal death were significantly increased when severe preeclampsia patients delivered before 34 weeks （P 〈 0.01 ）. The rate of light neonatal asphysia was increased when patients delivered between 34 and 37 weeks than after 37weeks （P 〈 0.05）. Fetal growth restriction was increased when patients delivered before 37 weeks than after 37 weeks （P 〈 0.05 ）. Incidence of pretem delivery in severe preeclampsia was 57%. The rate of perinatal death was 8.9%. Conclusions The rate of iatrogenic premature delivery is high in severe preeclampsia with poor perinatal outcome. Stopping gestation timely will reduce the incidence of perinatal＇s complications.

关 键 词：妊娠期高血压 重度子痫前期 围生儿结局 

分 类 号：R714.244[医药卫生—妇产科学]