4-氨基-3-氟苯酚的合成工艺研究  

Technology research on 4-amino-3-fluorophenol

作　　者：孙德群[1] 安永生 赖鹏翔[1] 吴利珍[1] 

机构地区：[1]山东大学威海分校海洋学院,山东威海264209 [2]威海秀水药物研发有限公司,山东威海264209

出　　处：《化学研究与应用》2008年第11期1526-1528,共3页Chemical Research and Application

摘　　要：4-amino-3-fluorophenol is synthesized by catalytic hydrogenation of the 1-fluoro-2-nitrobenzene in a reaction medium of inorganic acid and organic solvent,and then undergo the Bamberger rearrangement.The reaction conditions are optimized and a novel workup process suitable for production is obtained.4-amino-3-fluorophenol is synthesized by catalytic hydrogenation of the 1-fluoro-2-nitrobenzene in a reaction medium of inorganic acid and organic solvent, and then undergo the Bamberger rearrangement. The reaction conditions are optimized and a novel workup process suitable for production is obtained.

关 键 词：合成 催化氢化 中间体 

分 类 号：TQ630.4[化学工程—精细化工]