季铵化N,O-羧甲基壳聚糖的制备及其合成条件优化  

Preparation of Quaternized N,O-Carboxymethyl Chitosan and Optimization of the Synthetic Conditions

作　　者：杨蔚[1] 蔡照胜[2] 

机构地区：[1]江苏警官学院公安科技系,江苏南京210012 [2]盐城工学院化学与生物工程学院,江苏盐城224003

出　　处：《化学世界》2008年第11期667-670,679,共5页Chemical World

基　　金：国家自然科学基金资助项目(30471362);江苏省教育厅自然科学基础研究项目(06KJB150024)

摘　　要：以N,O-羧甲基化度为85.6%的羧甲基壳聚糖(CM-CTS)为原料,w=0.40的NaOH水溶液为催化剂,3-氯-2-羟丙基三甲氯化铵(CTA)为接枝改性剂,在异丙醇介质中制备了具有良好水溶性的两性壳聚糖-季铵化N,O-羧甲基壳聚糖;分别以产物对模拟废水中的Cd+和Cr(Ⅵ)的絮凝去除率为基准对两性壳聚糖的合成条件进行了优化;用IR和1H NMR对产物的结构进行了表征。研究结果表明产物Cr(Ⅵ)的去除率更适宜作为合成条件的优化基准,且对应的优化条件为:季铵化反应时间为10.0 h,反应温度为60.0℃,mNaOH/mCM-CTS=0.50,mCTA/mCM-CTS=1.5;在此条件下合成产物对Cr(Ⅵ)的最大絮凝去除率为93.16%,对Cd2+的最大絮凝去除率98.52%。A amphoteric chitosan with a higher solubility in water was prepared with 2-propanol as solvent, w= 0. 40 NaOH aqueous solution as catalyst, 3-chloro-2-hydroxypropyl trimethlyammonium chloride （CTA） as grafting agent and N,O-carboxymethylchitosan（CM-CTS） with carhoxymethyl degree of 85.6 as starting material. The synthetic conditions were optimized according to orthogonal experimens that based on the removal rate of Cd2＋ and Cr（Ⅵ）, respectively. The product was characterized by iR and 1H NMR. The experimental resuls showed the removal rate of Cr（Ⅵ ） could more suitably be regarded as the basis for the optimization of synthetic conditions. The optimized conditions were as follows the reaction time was 10. 0 h, the temperature was 60. 0℃ ,mNaOH/mCM-CTS=0.50,mCTAS/mCM-CTS=1.5. The maximum removal ratio of Cr（ VI ）and Cd2＋ for the product prepared under these conditions could reach up to 93.16% and 98.52;, resrpectively.

关 键 词：N O-羧甲基壳聚糖 3-氯-2-羟丙基三甲基氯化铵 接枝改性 季铵化N O-羧甲基壳聚糖 正交实验 

分 类 号：O636.1[理学—高分子化学]