国产缬草属4种药用植物镇静催眠作用的比较研究  

The Hypnotic and Sedative Actions of Four Medicinal Plants of Valeriana Genus in China

作　　者：黄宝康[1] 黄流清[2] 赵忠新[2] 秦路平[1] 郑汉臣[1] 

机构地区：[1]中国人民解放军第二军医大学药学院,上海200433 [2]中国人民解放军第二军医大学长征医院,上海200003

出　　处：《时珍国医国药》2008年第11期2710-2711,共2页Lishizhen Medicine and Materia Medica Research

基　　金：国家自然科学基金(No.30270152);上海-联合利华研究与发展基金(No.06SU07005)

摘　　要：目的研究比较国产缬草属4种药用植物的镇静催眠活性。方法通过观察其乙醇提取物对小鼠自主活动及戊巴比妥钠诱导小鼠睡眠时间的影响来评价其镇静催眠活性。结果中国缬草、宽叶缬草、蜘蛛香、黑水缬草均具有镇静催眠活性,以宽叶缬草和蜘蛛香活性较强。结论宽叶缬草及蜘蛛香药用植物等在镇静催眠方面具有开发利用潜力。Objective To investigate the sedative and hypnotic actions of four species of Valeriana L. Methods The hypnotic and sedative actions were observed by the spontaneous activity and pentobarbital sodium induced sleeping time in mice. Results They all had sedative and hypnotic actions, and V. officinalis var. latifolia and V. jatamansi showed higher activities. Conclusion - They have value in development of sedative and hypnotics.

关 键 词：缬草属 药用植物 镇静 催眠 

分 类 号：R285.5[医药卫生—中药学]