红细胞衰老过程中渗透脆性的变化  

The Changes of Osmotic Fragility of Erythrocytes in the Process of Aging

作　　者：宋立川[1] 刘红[1] 张久云[1] 喀蔚波[1] 吕智红 文宗耀 

机构地区：[1]华北煤炭医学院物理教研室,北京医科大学物理教研室

出　　处：《北京生物医学工程》1997年第3期178-180,共3页Beijing Biomedical Engineering

摘　　要：作者在用抗体诱发红细胞溶血法律立的红细胞在体衰老模型的基础上，研究了红细胞衰老过程中渗透脆性的变化。结果显示，随着红细胞年龄的增加，其渗透脆性增加。推论其渗透脆性的变化可能与红细胞膜结构及红细胞几何形状（即红细胞表面积与体积之比）的变化有关。Based on erythrocytes senile model in vivo, which developed by using antibody to induce acute homolysis of RBC, the authurs studied the change of osmotic fragility oferythrocytes. The result showed that the osmotic fragility increasing with the increase ofRBC age. It is deduced that the change of osmotic fragility may be related to the changes of the membrane structure and the geometric shapes (the ratios of surface areas tovolumes) of RBCs during their aging.

关 键 词：红细胞 老化 渗透脆性 

分 类 号：R331.141[医药卫生—人体生理学]