37例胃多原发癌的临床病理特征和诊治分析  

Analysis of clinical pathological features and treatment of 37 patients with gastric multiple primary carcinoma

作　　者：黄项武[1] 林芳英[1] 陈坚[2] 

机构地区：[1]福建省莆田学院附属医院普通外科,福建莆田351100 [2]解放军第八一医院普通外科,江苏南京210002

出　　处：《中国医疗前沿》2008年第10期20-21,共2页China Healthcare Innovation

摘　　要：目的探讨胃多原发癌的临床病理特征,探讨其合理的诊治方案。方法回顾性分析经病理证实的37例胃多原发癌的临床病理特征及其诊治情况,并结合文献进行分析和探讨。结果37例胃多原发恶性癌占同期收治原发胃恶性肿瘤的0.87%,其中同时多原发胃恶性肿瘤21例,异时多原发胃恶性肿瘤16例。癌灶部位以胃窦和贲门为多,病理类型以高或中分化腺癌多见。同时性胃多原发癌和异时性胃多原发癌的5年生存率分别为42.8%和52.9%。结论提高对多原发胃恶性肿瘤的诊断率主要依靠术前全面检查,术中仔细探查及术后的密切随访。早期诊断胃多原发癌并积极的手术治疗,可以提高生存率。Objective To investigate the clinicopathological features and reasonable diagnostic and therapeutic strategy of gastric multiple primary carcinoma （GMPC）.Methods All the patients were confirmed by pathology and had complete clinical data. The clinic pathological features and treatment of GMPC in 37 cases were analyzed retrospectively. Results The incidence of GMPC was 0.87% （37/4210） with 21 cases being synchronous carcinoma （SC） and 16 cases diagnosed as metachronous carcinomas （MC）. Most tumors were located in stomach antrum and cardia. The majority of Pathological types is high or moderately differentiated adenocarcinoma. The 5 year survival rate of SC and MC was 42.8% and 52.9% respectively. Conclusions The results indicated the importance of complete preoperative examination, careful intraoperative exploration and periodic postoperative surveillance. Early diagnosis and active radical resection can increase survival rate of GMPC.

关 键 词：胃癌 多原发癌 病理特征 治疗 

分 类 号：R735.2[医药卫生—肿瘤]