生物因子治疗慢性宫颈炎的疗效分析  

Effective Analysis on Biological Factors Treating Chronic Cervicitis

作　　者：刘玫鸰[1] 

机构地区：[1]南昌市第二医院妇产科,江西南昌330003

出　　处：《中国医疗前沿（学术版）》2008年第9期27-28,共2页China Healthcare Innovation

摘　　要：目的分析生物因子碱性成纤维细胞生长因子(bFGF)和α-干扰素栓(奥平)治疗慢性宫颈炎(宫颈糜烂)的疗效。方法217例慢性宫颈炎患者分成采用bFGF治疗的A组,α-干扰素栓治疗的B组,按照宫颈糜烂的I、II、III级和单纯型、颗粒型、乳头型观察两组的治疗效果。结果两组在I、II、III级和单纯型,颗粒型宫颈糜烂的治疗中无显著差异(P>0.05),但bFGF治疗的有效率均高于α-干扰素栓组。在乳头型宫颈糜烂的治疗中,B组疗效优于A组,P<0.01。结论慢性宫颈炎多由细菌,衣原体、支原体、病毒感染的急性宫颈炎转变而来,bFGF通过在损伤组织形成新生血管传递氧、营养、免疫因子、抗菌、抗炎、修复创面,达到治疗慢性宫颈炎中宫颈磨烂的效果。而α-干扰素栓,通过抗病毒,免疫调节的作用治疗宫颈糜烂,我们的研究表明,这两种生物因子治疗慢性宫颈炎均有比较理想的效果。Objective To analyze effects on basic fibroblast growth factor （bFGF）and α-interferon suppositium treating chronic cervictitis. Methods 217 patients with chronic cerictitis were divided into A group cured with bFGF and B group cured with α-interferon suppository to observe their treatment effect according to I,II,III grade and simple, gramular, papillate form in cervical erosion. Results The curative effect in I, LIII grade and simple, granular form of cervical erosion was no significant difference in two groups （P〉0.05）, but effective rate of A graup was superior to B group. B granp was obvious better than A in papillate form cervical erosion （P〈0.01） Conclusion Chronic cervicititis is most attacted from acute cervicititis infected by bacteria, choamydia,mycoplasma and virus, bFGF and α-interfrom treated chronic cervicititis by forming new blood vesset, transmiting oxygen, nutrition, immune factocs, anti-inflammation, antibaeteriam, repairing wound and anti-virus, immunoregulation in njury tissue. The two biological factors had a better cuative effect in our study.

关 键 词：慢性宫颈炎 碱性成纤维细胞生长因子 Α-干扰素栓 

分 类 号：R711.32[医药卫生—妇产科学]