BIS监测在机械通气患者镇静深度评价中的价值  

The Value of Bispectral Index Monitor in Assessing the Depth of Sedation of Ventilated Patients

作　　者：张川[1] 李孝锦[1] 李晓玉[1] 郑碧霞[1] 程金川[1] 祃红原[1] 

机构地区：[1]成都市第三人民医院综合监护室,四川成都610031

出　　处：《华西医学》2008年第1期41-42,共2页West China Medical Journal

基　　金：成都市科学技术局2007年攻关计划重点资助项目(成科计[2007]1号)

摘　　要：目的:探讨脑电双频指数(BIS)监测在机械通气患者镇静深度评价中的价值。方法:选取15例机械通气患者,静脉注射咪唑安定达到SAS评分3～4分,持续或间断给药维持镇静深度,记录患者每2小时的SAS镇静分级评分及BIS,观察24小时。比较SAS评分与BIS值的相关性。计算BIS的敏感度和特异度,根据ROC曲线和BIS评价镇静深度的敏感度和特异度,寻找最适BIS值。结果:随镇静深度的加深,BIS明显降低,BIS与SAS评分呈正相关(r=0.662,P<0.05);SAS评分3～4分(镇静适度)时对应的BIS临界值为69.5～79。结论:BIS监测与SAS评分之间具有良好的相关性,能同步客观地监测机械通气患者的镇静深度,具有一定的临床诊断价值。Objective：To determine the value of the bispectral index（BIS）monitor in assessing the depth of sedation of ventilated patients.Methods：Select 15 cases of mechanical ventilated patients for intravenous injection of midazolam to SAS score of 3-4 points,with continuous or intermittent administration to maintain sedative depth.To record sedative scales of SAS and BIS every 2 hours during 24 hours and compare correlation between SAS score and BIS value.Compute sensitivity and specificity of BIS.To evaluate the sensitivity and specificity of sedation depth based on ROC curve and BIS.Work out critical value of BIS under appropriate sedative degree.Results：With deepening of sedative depth,the BIS apparently decreases.BIS is positive relative to SAS scale（r=0.662,P〈0.05）.When the SAS score is 3-4 points（in appropriate sedative degree）,the corresponding critical value of BIS is 69.5～79.Conclusion：BIS monitoring has good correlation with SAS scale.It can simultaneously and objectively monitor sedative depth of mechanically ventilated patients.It has certain clinical diagnosis value.

关 键 词：脑电双频指数 SAS评分 镇静深度 机械通气 

分 类 号：R614[医药卫生—麻醉学]