He-Ne激光、高流量吸氧及牛血去蛋白治疗外伤性鼓膜穿孔  

He-Ne Laser,O_2 inhalation and de-proteinized calf blood extracts applied to tympanic membrane perforation induced by trauma

作　　者：刘继荣[1] 李大佑[1] 李冬梅[1] 

机构地区：[1]济南市第三人民医院耳鼻咽喉科,济南250101

出　　处：《山东大学耳鼻喉眼学报》2008年第5期424-426,共3页Journal of Otolaryngology and Ophthalmology of Shandong University

基　　金：济南市科技局科研基金资助项目(立项项目)(2008)

摘　　要：目的评价He-Ne激光、高流量吸氧配合药物治疗外伤性鼓膜穿孔的疗效。方法将外伤性鼓膜穿孔患者112例随机分为治疗组(42例43耳)、对照A组(40例40耳)、对照B组(30例30耳)。治疗组应用He-Ne激光局部照射、配合药物治疗同时高流量吸氧;对照A组自然恢复、对照B组采用鼓膜贴补治疗。于治疗2、4周后分别观察鼓膜穿孔的愈合情况。随访3个月。结果治疗组治疗2、4周后治愈率分别为71.43%、95.24%,明显高于对照A组(P<0.01),与对照B组比较,差异无统计学意义。结论He-Ne激光、高流量吸氧配合药物治疗外伤性鼓膜穿孔疗效良好,鼓膜愈合时间缩短,治愈率高。Objective To assess the effect of He-Ne laser,O2 inhalation in combination with de-proteinized calf blood extracts in treatment of tympanic membrane perforation induced by trauma.Methods 112 cases of tympanic membrane trauma perforations were randomly divided into the experimental group and the control group A and the control group B.42 patients（43 ears） in the experimental group were treated with He-Ne laser,O2 inhalation and medicines.40 patients（40 ears） in control group A mended by themselves.30 patients（30 ears） in control group B were treated by the tympanic membrane patching method.Also the three groups were routinely treated with antibiotics.Tympanic membrane trauma perforations were observed after 2 and 4 weeks of treatments and followed up for 3 months.Results Curative rates at 2 and 4 weeks in the experimental group were 71.43% and 95.24%,which were significantly higher than those（17.5% and 45%）in the control group A（both P〈0.01,χ2 test）.There were no statistical significances（χ2=3.429 and χ2=1.683,both P〉0.05） between the experimental group and the control group B.Conclusions He-Ne laser,O2 inhalation and medicines can increase the therapeutic effectiveness of tympanic membrane trauma perforation,shorten the period of healing and improve the curative rate.

关 键 词：外伤性鼓膜穿孔 HE-NE激光 高流量吸氧 治疗 

分 类 号：R764.29[医药卫生—耳鼻咽喉科]