银线草化学成分的研究(Ⅰ)  

Study on chemical constituents of Chloranthus japonicus Sieb.(Ⅰ)

作　　者：夏永刚[1] 杨炳友[1] 吕邵娃[1] 孙光日[1] 张洪财[1] 匡海学[1] 

机构地区：[1]黑龙江中医药大学,黑龙江哈尔滨150040

出　　处：《中医药信息》2008年第6期30-31,共2页Information on Traditional Chinese Medicine

基　　金：国家自然科学基金资助项目(30772720);黑龙江省教育厅科学技术研究项目(11521262)

摘　　要：目的：研究银线草（Chloranthus japonicus Sieb．）抗肿瘤有效部位的化学成分。方法：利用正、反相柱色谱等方法等进行分离，依据理化性质和各种波谱数据进行结构鉴定。结果：从银线草抗肿瘤有效部位分离并鉴定了3个化合物，分别为嗪皮啶（fraxidin）（Ⅰ）、异嗪皮啶-7-O-β-D-葡萄糖苷（isofraxidin-7-Oβ-D—glucopyranoside）（Ⅱ）和盾叶夹竹桃苷（androsin）（Ⅲ）。结论：化合物Ⅰ～Ⅲ均为首次从银线草中分离得到。Objective: To study chemical constituents of the active parts for anti-tumor from Chloranthus japonicus Sieb..Methods: Three compounds were isolated from C.japonicus through repeated silica gel and ODS column chromatography.Their structures were determined on the basis of the spectroscopic analysis.Results: Fraxidin(Ⅰ),isofraxidin-7-O-β-D-glucopyranoside(Ⅱ) and androsin(Ⅲ) were isolated from C.japonicus.Conclusion: CompoundsⅠ-Ⅲ were isolated from C.japonicus for the first time.

关 键 词：银线草 嗪皮啶 异嗪皮啶-7-O-β-D-葡萄糖苷 盾叶夹竹桃苷 化学成分 

分 类 号：R284.1[医药卫生—中药学]