碳纳米管的细胞生物学效应  

CELLULAR BIOLOGICAL EFFECTS OF CARBON NANOTUBES

作　　者：高素莲[1] 李秀娥[2] 翟淑梅[2] 曲广波[2] 张斌[2] 

机构地区：[1]山东大学环境研究院,济南250100 [2]山东大学药学院,济南250012

出　　处：《环境化学》2008年第6期831-834,共4页Environmental Chemistry

基　　金：山东省自然科学基金项目(Y2006B19)

摘　　要：在碳纳米管生物学效应的研究中,细胞实验比动物实验更易于控制并且耗费较低,目前已取得了多方面的进展.本文从碳纳米管的细胞毒性、现行毒性评价方法的可靠性及细胞对碳纳米管的摄入机制三个方面进行介绍,并对该领域的研究前景进行了展望和分析.In the last years, carbon nanotubes （CNTs） have been intensively investigated for its wide potential applications especially in biomedicine because of the unique physicochemical properties. Thus, it is imperative to study effects of CNTs on biological systems. Compared to animal studies, cellular testing is easier to control and less expensive. Several groups have reported the cellular biological effects of CNTs and lots of information has been obtained. This review mainly presents cytotoxicity of CNTs, the reliability of the cytotoxicity evaluation methods and the cellular uptake mechanism.

关 键 词：碳纳米管 细胞生物学 细胞毒性 物理化学性质 

分 类 号：TB383.1[一般工业技术—材料科学与工程]