张力侧与压力侧不同程度皮质缺损对骨干生物力学性能的影响  

Biomechanical changes in long tubular bone due to different cortical bone defects at tension/compression sides

作　　者：陈建海[1] 姜保国[1] 张殿英[1] 付中国[1] 

机构地区：[1]北京大学人民医院创伤骨科,北京大学交通医学中心,100044

出　　处：《中华创伤骨科杂志》2008年第11期1049-1052,共4页Chinese Journal of Orthopaedic Trauma

基　　金：国家重点基础研究发展计划（973计划）项目（2005CB522604）

摘　　要：目的探讨皮质缺损程度和位置对骨干生物力学性能的影响。方法山羊股骨标本72个，分别按照骨干冠状面直径的10％、20％、30％、40％和50％制作张力侧和压力侧的皮质环形缺损，正常羊骨作为健康对照。对标本进行三点弯曲测试，力学指标包括最大负荷、最大功耗和弹性模量。记录每个标本的冠状面和矢状面直径，张力侧和压力侧皮质厚度。结果各组标本的外径和皮质厚度差异均无统计学意义（P〉0．05）。张力侧皮质缺损在50％亚组的最大负荷较健康对照组显著降低（P〈0．05），压力侧皮质缺损在50％、40％和30％亚组的最大负荷较健康对照组显著降低（P〈0．05）；张力侧皮质缺损在50％、40％和30％亚组的最大功耗较健康对照组有显著降低（P分别为0．000，0．000，0．015），压力侧皮质缺损在各个缺损组的最大功耗均较健康对照组显著降低（P均为0．000）。张力侧、压力侧皮质缺损的冠状径、矢状径、压力侧皮质厚度、弹性模量及张力侧皮质缺损的张力侧皮质厚度与健康对照组比较差异均无统计学意义（P〉0．05），压力侧皮质缺损的张力侧皮质厚度与健康对照组比较，差异有统计学意义（P〈0．05）。结论皮质缺损对骨干力学性能有影响，张力侧和压力侧皮质缺损对骨干力学性能的影响不同。Objective To explore biomechanical changes in long tubular bone due to different cortical bone defects at sizes and locations. Methods Seventy-two femurs of adult goat were used in this study. Circular cortical defects were created by drills at the mid-point of the long tubular bone at tension/ compression sites. They were divided into tension and compression groups accordingly. Diameters of the defects were made as 10%, 20%, 30%, 400/0 and 50% of the coronal diameter. Three-point bending test was performed for each sample. Biomechanical parameters were maximum strength, maximum work and elastic module. The diameters of coronal and sagittal planes, and the thickness of cortical bone at tension and com- pression sites were recorded for each sample. Normal goat femurs were tested as controls. Results The diameters and thicknesses of the cortical bone were insignificantly different between groups. The maximum strength significantly decreased in the group with 50% defect at tension side and in the groups with 30%, 40%, 50% defects at compression side. The maximum work significantly decreased in groups with 30%, 40%, 50% defects at tension side and in grOups with 10% -50% defects at compression side. The elastic module showed no significant difference among tension groups, compression groups and the control group. Conclusions Cortical bone defects may have influence on biomechanical performance of the long tubular bone. The influence may be different depending on the tension site or the compression site.

关 键 词：骨缺损 股骨 山羊 生物力学 

分 类 号：R687.3[医药卫生—骨科学]