密穗马先蒿对耐力运动小鼠红细胞参数、抗氧化和免疫功能的影响  

Effects of pedicularis densispica on morphology parameters,antioxidation and immunity capacity in erythrocyte of mice performing endurance exercises

作　　者：文质君[1] 陈筱春[1] 朱梅菊[1] 赖小兵[1] 

机构地区：[1]湛江师范学院体育系,广东524048

出　　处：《中国康复医学杂志》2008年第11期1022-1024,共3页Chinese Journal of Rehabilitation Medicine

基　　金：湛江师范学院自然科学基金资助项目(L0519)

摘　　要：目的:研究密穗马先蒿对耐力运动小鼠红细胞形态参数、红细胞抗氧化和免疫黏附功能的影响。方法:4周龄昆明种小鼠随机分为对照组、运动组、阳性对照组、密穗马先蒿组。运动组、阳性对照组和密穗马先蒿组进行6周的游泳训练,最后一次进行力竭游泳。力竭游泳后采用眼球取血,EDTA抗凝,测定红细胞参数、红细胞抗氧化功能及红细胞免疫黏附功能等指标。结果:实验6周后,密穗马先蒿组小鼠RBC、Hb、HCT、RBC-SOD活性和RBC-C3bR明显高于运动组(P<0.05),而MCV、RDW、RBC-ICR和RBC-MDA含量低于运动组(P<0.05)。结论:密穗马先蒿具有改善耐力运动引起的小鼠红细胞的损伤,保护小鼠红细胞的完整性,提高耐力运动小鼠红细胞的抗氧化能力和免疫功能等作用。Objective：To study the effects of pedicularis densispica on erythroeyte parameters, antioxidation and immunity capacity in endurance exercises mice. Method： The four-week old mice were divided randomly into 4 groups： control group, training group, positive control group and pedieutaris densispica group. The mice in training group, positive control group and pedicularis densispiea group had swimming exercises for 6 weeks, and at the last times they swam exhaustively. The morphology parameters of erythroeyte, function of erythrocyte immune and antioxidation were tested after swimming exhaustively. Result： It showed that the pedicularis densispica was effective in increasing RBC,Hb,HCT, RBC-C3bR and the activity of RBC-SOD （P〈0.05）, and decreasing MCV, RDW,RBC-ICR and RBC-MDA content （P〈0.05）, comparing to training group. Conclusion：It indicated that pedieulafis densispiea was effective to protect morphological integrity of erythrucyte from injury by endurance exercises,and improved antioxidalion and immunity capacity of erythrocyte of mice after endaranee exercises.

关 键 词：密穗马先蒿 红细胞参数 红细胞自由基代谢 红细胞免疫黏附功能 

分 类 号：R285[医药卫生—中药学]