血压管理对脑血管反应性的影响  

The impact of management of blood pressure on cerebrovascular reactivity

作　　者：张旋[1] 张妍 吕伟[1] 赵贺玲[1] 曹秉振[1] 

机构地区：[1]济南军区总医院神经内科,山东济南250031

出　　处：《实用医药杂志》2008年第11期1283-1284,共2页Practical Journal of Medicine & Pharmacy

摘　　要：目的采用经颅多普勒超声(TCD)屏气试验评价血压控制良好患者及血压控制不良患者的脑血管反应性(CVR),探讨血压管理与CVR的关系。方法采用TCD屏气试验分别测定血压控制良好A组患者96例(血压均得到良好控制在3个月以上),血压控制不良患者79例(未服药或未规则服药,3个月内多次血压测量均明显升高)。比较屏气前后大脑中动脉(MCA)流速增长的百分数,即屏气指数(BHI),评价CVR指标。结果血压控制良好患者组CVR显著高于血压控制不良患者组(P<0.05)。结论长期血压管理对改善脑血管反应性有重要意义,进而可减低卒中的发生。Objective To assess the cerebrovascular reactivity （CVR） in patients with well-controlled hypertension and those with non-controlled hypertension by means of transcranial Doppler uhrasonography （TCD） with breath-holding maneuver, so as to explore the relationship between the management of blood pressure and CVR. Methods Ninety-six patients with well controlled hypertension and 79 patients with non-controlled hypertension were enrolled into the study. Using TCD and breath-holding technique, BHI value, which was the percentage increase in middle cerebral artery （MCA）blood flow velocity during breath-holding in healthy and patients with various risk-factors of cerebrovascular disease were observed and compared as index of CVR assessment. Result The patients with well controlled hypertension had a significantly increased CVR than that with non-controlled hypertension. Conclusion The long-term control of hypertension might be benefit to CVR, and consequentely decrease the reoccurence of stroke.

关 键 词：血压管理 脑血管反应性 屏气试验 经颅多谱勒超声 高血压病 

分 类 号：R445.1[医药卫生—影像医学与核医学] R743.1[医药卫生—诊断学]