急性脑出血并发应激性溃疡患者血浆及胃液中胃动素水平的研究  

Study of motilin level of plasma and gastric juice in the patients with acute cerebral hemorrhage complicated with stress ulcer

作　　者：孙飞[1] 赵建平[1] 王博[1] 

机构地区：[1]徐州市中心医院脑外科,江苏徐州221009

出　　处：《现代医药卫生》2008年第23期3490-3491,共2页Journal of Modern Medicine & Health

摘　　要：目的:研究急性脑出血并发应激性溃疡(SU)患者血浆胃液中胃动素(motilin,MTL)水平,探讨MTL在SU发病过程中的作用。方法:选择35例急性脑出血并发SU患者,在出现SU的当天、第三至五天、第十至十四天,同时采血液及胃液并应用放射免疫的方法测定MTL水平,并与30例对照组比较。结果:急性脑出血并发SU的患者当天血浆及胃液MTL水平均明显高于对照组(P<0.05);第三至五天与发病当天比较,有增高趋势,但无统计学意义(P>0.05),与对照组比较明显增高(P<0.01);第十至十四天,降至正常水平(与对照组相比P>0.05)。SU患者血浆与胃液中MTL水平相比无明显差异(P>0.05)。结论:急性脑出血患者SU发生与血浆及胃液中MTL水平增高有关。Objective：To observe the motilin （MTL） level of plasma and gastric juice in the patients with acute cerebral hemorrhage complicated with stress ulcer and its clinical significance. Methods：To detect the MTL level of plasma and gastric juice in 35 patients with acute cerebral hemorrhage complicated with stress ulcer by radioimmunoassay in the first day,the 3-5 day and the 10-14 day and contrast with the 30 patients as a control group. Results：The MTL levels of plasma and gastric juice in stress ulcer patients were significandy higher than those in control group （P〈0.05） in the first day;Those were higher in the 3-5 day than in the fast day,but there were no statistical signifieance（P〉0.05）; and those were significantly higher than in control group（P〈0.01）;Those descended to the normal level in the 10-14 day （P〉0.05）. In stress ulcer patients, there was no significant difference between the plasma MTL level and gastric juice MTL level（P〉0.05）.Conclusion ：Stress ulcer after acute cerebral hemorrhage correlates with increased MTL in the plasma and gastric juice.

关 键 词：应激性溃疡 血浆 胃液 胃动素 脑出血 

分 类 号：R6[医药卫生—外科学]