全髋关节置换术中局部注射混合镇痛液疗效的临床对照试验  

Observation of the efficacy of local multimodal analgesic drugs injection in total hip arthroplasty

作　　者：翁文杰[1] 王锋[1] 陈东阳[1] 袁涛[1] 徐志宏[1] 蒋青[1] 

机构地区：[1]南京大学医学院附属鼓楼医院骨科,江苏南京210008

出　　处：《中国骨伤》2008年第11期834-836,共3页China Journal of Orthopaedics and Traumatology

摘　　要：目的:研究全髋关节置换术中向关节周围局部注射混合镇痛液的疗效。方法:将76例行全髋关节置换术的患者分成2组,38例患者术中关节周围注射混合镇痛液,另38例不注射。术后采用直观模拟疼痛量表(VAS)评估患者疼痛程度;所有患者术后24h内使用患者自控镇痛泵(PCA),于不同时间点分别记录PCA的用量。结果:在麻醉后恢复室及术后4h,患者VAS疼痛评分注射组比对照组明显低。患者PCA使用量,与对照组6h及12h相比,注射组使用量明显少;术后24h内PCA使用总量注射组也比对照组明显少。注射组患者未观察到任何与混合镇痛液相关的不良反应。结论:全髋关节置换术中向关节周围注射混合镇痛液能够显著降低患者术后疼痛并减少镇痛泵的用量。Objective ：To study the efficacy of periarticular muhimodal analgesic drugs injection in total hip arthroplasty. Methods： Seventy-six patients undergoing total hip arthroplasty were randomly divided into two groups, 38 patients received periarticular intraoperative injection of muhimodal analgesic drugs, and others not do. Pain of patients were evaluated with a visual analog scale postoperatively,and all patients received patient-controlled analgesia for 24 hours after surgery. The consumption of patient-controlled analgesia was recorded at different time-points. Results： Compared to the control group, visual analog scores for pain of the patients of injected group had significantly lower in the post-anesthetic-care unit and four hours after surgery. Patients of the injected group used significantly less patient-controlled analgesia at 6,12 hours, and over the first 24 hours after surgery than the control group. No adverse effects resulted from the multimodal analgesic drugs were noted in the injected group. Conclusion：Periarticular injection of multimodal analgesic drugs in total hip arthroplasty can significantly reduce the postoperative pain of patients and the consumption of patient-controlled analgesia.

关 键 词：关节成形术 置换 髋 镇痛 临床对照试验 

分 类 号：R687.4[医药卫生—骨科学] R752.53[医药卫生—外科学]