Albumin liver dialysis as pregnancy-saving procedure in cholestatic liver disease and intractable pruritus  

作　　者：Maud Lemoine Aurélie Revaux Claire Francoz Guillaume Ducarme Sabine Brechignac Emmanuel Jacquemin Michèle Uzan Nathalie Ganne-Carrié 

机构地区：[1]Service d'Hépatologie, Hospital Jean-Verdier, Bondy 93140, France [2]Service de Gynécologie Obstétrique, Hospital Jean-Verdier, Bondy 93140, France [3]Service d'Hépatologie, Hospital Beaujon, Clichy 92110, France [4]Service de Médecine interne, Hospital Avicenne, Bobigny 93000, France [5]Service d'Hépatologie pédiatriqueH?pital Kremlin-Bicêtre, Le Kremlin-Bicêtre 94270, France

出　　处：《World Journal of Gastroenterology》2008年第42期6572-6574,共3页世界胃肠病学杂志（英文版）

摘　　要：Progressive familial intrahepatic cholestasis type 3 (PFIC3) is a rare cholestatic liver disease. Such liver disease can get worse by female hormone disorder. Albumin dialysis or Molecular Adsorbent Recirculating System (MARS) has been reported to reverse severe cholestasis-linked pruritus. Here, we report the first use of MARS during a spontaneous pregnancy and its successful outcome in a patient with PFIC3 and intractable pruritus. Albumin dialysis could be considered as a pregnancy-saving procedure in pregnant women with severe cholestasis and refractory pruritus.Progressive familial intrahepatic cholestasis type 3 （PFIC3） is a rare cholestatic liver disease. Such liver disease can get worse by female hormone disorder. Albumin dialysis or Molecular Adsorbent Recirculating System （MARS） has been reported to reverse severe cholestasis-linked pruritus. Here, we report the first use of MARS during a spontaneous pregnancy and its successful outcome in a patient with PFIC3 and intractable pruritus. Albumin dialysis could be considered as a pregnancy-saving procedure in pregnant women with severe cholestasis and refractory pruritus.

关 键 词：Albumin dialysis Intractable pruritus PREGNANCY Cholestatic liver disease 

分 类 号：R575[医药卫生—消化系统]