谷胱甘肽在不育治疗和辅助生育医学中的价值  

Glutathione and Male Reproduction

作　　者：侯保山[1] 王宗丹[2] 商学军[1] 

机构地区：[1]南京军区南京总医院男科,江苏南京210002 [2]南京医科大学,03级医学检验专业江苏南京210029

出　　处：《中华男科学杂志》2008年第11期1023-1026,共4页National Journal of Andrology

摘　　要：还原型谷胱甘肽(GSH)是哺乳动物细胞内最为丰富的非蛋白巯基类物质,其在机体内广泛分布,具有重要的生理作用,包括蛋白质和DNA的合成、氨基酸的转运等,其中最重要的功能是保护细胞对抗氧化损伤,并在很多疾病的治疗中有重要的临床价值。近年来研究发现,GSH在男性生殖系统中也广泛存在,并在男性不育治疗中也具有一定意义,本文就其在男性生殖系统中的分布、作用及临床治疗价值作一综述。Reduced glutathione （GSH） , the most abundant non-protein thiol in mammalian cells, exists extensively in the human body and plays a key role in many biological processes, including the synthesis of proteins and DNA and the transport of amino acids, especially in protecting cells against oxidation. GSH also shows its important clinical value in the treatment of many diseases. It has been reported that GSH also widely exists in the male reproductive system and has a therapeutic role in male infertility. The objective of this review is to summarize the distribution of GSH in the male reproductive system and its therapeutic value for male infertility.

关 键 词：谷胱甘肽 睾丸 附睾 精子 

分 类 号：R711.6[医药卫生—妇产科学]