阻塞性睡眠呼吸暂停低通气综合征患者行为干预的效果研究  

Effect of behavioral therapy program on patients with obstructive sleep apnea hypopnea syndrome

作　　者：李菁[1] 李峥[1] 李五一[2] 霍红[2] 李静宜[3] 李韬[2] 

机构地区：[1]北京协和医学院护理学院,北京市100730 [2]北京协和医院 [3]北京阜外心血管专科医院

出　　处：《中华护理杂志》2008年第12期1083-1087,共5页Chinese Journal of Nursing

摘　　要：目的探讨16周行为干预对阻塞性睡眠呼吸暂停低通气综合征患者的影响。方法将48例患者随机分为实验组和对照组各24例。两组均接受一般性行为指导,实验组另接受16周行为干预。在干预的第4周和第16周分别对两组患者的生理、睡眠、症状、生活质量和依从性等指标进行比较评价。结果实验组干预的第16周体重指数与对照组差异显著(P<0.05),主观症状、日间嗜睡症状、生活质量的社会交往、症状维度和总体的改善与对照组的差异非常显著(P<0.01)。实验组干预第16周时依从性(81.8%)显著高于第4周时(36.4%)。结论接受行为干预的患者依从性良好,其体重指数、症状和部分生活质量显著改善,但对睡眠和其他生理指标的改善效果需进一步研究。Objective To investigate the effect of a behavioral therapy program on patients with obstructive sleep apnea hypopnea syndmme（OSAHS）. Method Forty-eight obese patients with moderate to severe OSAHS were assigned into intervention group（n=24） or control group（n=24）. The control group was given a general behavioral instruction. The intervention group was given 16-week behavioral therapy. Polysomnographie index,physiological index,daytime somnolence and quality of life were measured at 4 week and 16 week after behavioral therapy delivered. Results At 16 week after therapy delivered,physiological index of intervention group decreased a lot ,but there was no significant difference by interclass comparison except BMI （P〈0.05）. Subjective symptoms,ESS score,the dimensions of social interactions,symptom and the total score of the QOL improved significantly（P〈0.01 ） for intervention group eompared with control group. The compliance of intervention group was significantly higher when compared at 16 week after intervention（81.8%） with 4 week after intervention（36.4%）. Conclusions The compliance of behavioral therapy was good. Behavioral therapy could significantly improve BMI,symptoms and quality of life of OSAHS patients,but the effect on polysomnographic index and other physiological index still need further exploration.

关 键 词：睡眠呼吸暂停 阻塞性 行为疗法 生活质量 病人依从 

分 类 号：R473.76[医药卫生—护理学]