“一步法”制备纳米相丝素蛋白/羟基磷灰石生物复合材料  

Preparation of nano silk fibroin/hydroxyapatite biological composite by "one-step" method

作　　者：王刚[1] 姚金波[1] 周旭光[2] 盛楠 

机构地区：[1]天津工业大学纺织学院,天津300160 [2]天津工业大学材料科学与化学工程学院,天津300160 [3]天津市德凯化工有限公司,天津300160

出　　处：《复合材料学报》2008年第6期136-139,共4页Acta Materiae Compositae Sinica

基　　金：天津市自然基金资助(05YFJMJCO4700)

摘　　要：系统分析了羟基磷灰石(HA)的制备方法和丝素蛋白纤维(SF)的溶解方法,提出一种制备纳米丝素蛋白/羟基磷灰石生物复合材料(SF/HA)的新型反应复合方法——"一步法"。并对由"一步法"制得的SF/HA分别进行了钙磷比测定、红外光谱测试、透射电镜观察和X射线衍射测试。结果表明:SF/HA中的钙磷比是1.6692,与标准HA中的钙磷比1.67一致;SF/HA中同时含有SF和HA中各自的官能团;SF/HA的晶粒横向尺度小于100 nm,SF/HA呈针状或柱状晶粒,SF和HA能够形成复合;SF/HA的晶型属于六方晶系,当SF在SF/HA中所占质量分数为10%时,晶胞参数a=b=9.0319,c=7.0148,沿c轴方向平均晶粒尺寸是230.7645。"一步法"制备SF/HA具有合理性和可行性。On the basis of analyzing the preparation method of hydroxyapatite （HA） and the diffluence method of silk fibroin fibre （SF）, a ＂one-step＂ method that is used to prepare nano hydroxyapatite/silk fibroin biology composite （SF/HA） was put forward. The SF/HA composite was observed and tested by FTIR, TEM and XRD. The ratio of calcium to phosphorus in the SF/HA composite was tested by the chemical method. The results show that the ratio of calcium to phosphorus in the SF/HA composite is 1. 6692, which is the same as 1.67 in HA. The function groups in both HA and SF were discovered in the SF/HA composite. The SF/HA composite crystal particle is of spiculate or column configuration. The crystal size of the SF/HA composite is less than 100 nm in the horizontal direction. The HA and SF composite can come into being. The HA/SF composite is hexahedron crystal. When the mass fraction of SF in SF/HA was 10%, the crystal cell parameter of the SF/HA composite crystal is a= b=9.0319 A, c=7.0148 A. The average crystal size of SF/HA along the c axes direction is 230. 7645 A. So the ＂one-step＂ method is rational and feasible.

关 键 词：羟基磷灰石 丝素蛋白 生物复合材料 

分 类 号：TB383[一般工业技术—材料科学与工程]