蛇胸腺的神经内分沁细胞  

THE NEUROENDOCRINE CELLS IN THYMUS OF SNAKE RHABDOPHIS TIGRINA

作　　者：李丕鹏[1,2,3] 邓泽沛[1,2,3] 王平 

机构地区：[1]烟台师范学院生物系暨生物研究所 [2]中国农业大学动物医学院 [3]北京大学生命科学学院

出　　处：《解剖学报》1997年第4期429-432,I014,共5页Acta Anatomica Sinica

基　　金：国家自然科学基金

摘　　要：为了进一步了解蛇胸腺实质组织的内分泌特性，用１６种激素和神经递质的抗血清对其进行了免疫组织化学观察。结果显示，蛇胸腺含有一些呈ＣＣＫ、ＣＲＦ、Ｅｎｄ、Ｇａｓ、Ｇｌｕ、ＧＲＰ、５－ＨＴ、Ｍｏｔ、Ｎｅｕ和ＳＳ免疫反应的细胞，其中以ＣＣＫ、ＣＲＦ、５－ＨＴ、Ｇａｓ、Ｍｏｔ和ＳＳ反应较强，ＣＣＫ、ＣＲＦ、５－ＴＨ和Ｇａｓ阳性细胞较多。这类细胞形态结构与胸腺上皮细胞明显不同，而与弥散神经内分泌细胞相似。这表明蛇胸腺实质中存在一类具有神经内分泌特性的细胞，应属于弥散神经内分泌系统。In order to explore the neuroendocrine properties of the thymus gland,the immunohistochemical localization of sixteen kinds of endocrine hormones and neurotransmitters in snake(Rhabdophis tigrina)were observed.The results showed that the cells were CCK,CRF,End,Gas,Glu,5 HT,GRP,Mot,Neu and/or SS positive and GIP,Sec,Sp,VIP,GH and thyroid globulin negative.The positive cells were scattered in the thymic medulla and were mainly elliptical in shape which were differnet from thymic epithelial cells.It indicated that these cells were neuroendocrine in the properties and belonged to the diffuse neuroendocrine system,like the neuroendocrine cells of gastrointestinal tract and pulmonary tract.

关 键 词：胸腺 神经内分泌细胞 免疫组织化学 蛇 

分 类 号：R329.453[医药卫生—人体解剖和组织胚胎学] Q959.620.4[医药卫生—基础医学]