小剂量咪达唑仑在无痛苦胃镜检查中的应用  

STUDY ON APPLICATION OF MIDAZOLAM INJECTION IN PAINLESS GASTROSCOPY

作　　者：林尤冠[1] 曾仕平[1] 莫青[1] 蔡笃雄[1] 王铿[1] 

机构地区：[1]海南医学院附属医院消化内科,海口570102

出　　处：《现代预防医学》2008年第23期4744-4745,4748,共3页Modern Preventive Medicine

摘　　要：[目的]研究咪达唑仑针在无痛苦胃镜检查中的镇静效果和安全性。[方法]无痛苦组患者200例给予静脉注射小剂量咪达唑仑针(0.05mg/kg)后行胃镜检查,对照组200例按常规检查方法进行胃镜操作,比较两组胃镜检查中患者的反应和感受,观察两组胃镜检查前后患者心率、动脉血压及血氧饱和度变化。[结果]无痛苦组患者咽部不适、恶心、呕吐及躁动的发生率均明显低于对照组(P﹤0.01),满意度好。[结论]小剂量咪达唑仑针应用于无痛苦胃镜检查起效快、恢复快,且安全、有效。[Objective] To study the efficacy and safety of midazolam in painless gastroscopy. [Methods] Two hundred patients in painless group were given 0.05mg/kg intravenous midazolam before gastroscopy, two hundred patients in control group were performed by routine gastroscopy. Patient＇s reaction and feeling were compared between the two groups during gastroscopy. The changes of blood pressure, heart rate and oxygen saturation were measured. [ Results] The incidences of restlessness, nausea, vomiting, and guttural discomfort in painless group were obviously lower than those of the control group （P 〈 0.01 ）. Compared with the blood pressure, heart rate and oxygen saturation in painless group before gastroscopy, there were no differences during gastroscopy （P 〉 0.05）. [ Conclusion ] With intravenous use of midazolam, gastroscopy can be performed effectively and safely.

关 键 词：咪达唑仑针 胃镜检查 镇静 

分 类 号：R445[医药卫生—影像医学与核医学]