丙泊酚复合芬太尼用于门诊无痛人工流产的临床观察  

Clinical observation of propofol combined with fentanyl in induced abortion

作　　者：李细平[1] 

机构地区：[1]娄底市中心医院产科,湖南娄底417000

出　　处：《国际医药卫生导报》2008年第23期50-52,共3页International Medicine and Health Guidance News

摘　　要：目的观察丙泊酚复合芬太尼用于门诊无痛人工流产术的镇痛效果及不良反应。方法选择门诊ASAⅠ-Ⅱ级早期妊娠需人工流产者80例，随机分成两组（每组40例）。研究组40例为首剂芬太尼1μg／kg，复合丙泊酚2mg／kg；对照组40例为首剂丙泊酚2mg／kg。观察比较两组术前、诱导2min、术后的BP、HR、R、SpO2及镇痛效果。结果研究组镇痛效果好且丙泊酚用量少，差异有统计学意义（P〈0．01）。两组不艮反应差异不明显。结论丙泊酚复合芬太尼可安全用于门诊无痛人工流产术，且镇痛效果好，非常有效地抑制或减轻患者术后宫缩痛，且不影响清醒质量，提高了患者满意率。Objective To observe the analgesia and adverse effect of propofol combined with fentanyl in induced abortion in clinic se;vice. Methods 80 early pregnant women voluntary to have painless artificial abortion, who had no contraindication to surgery and to misoprostol ,were randomly divided into 2 groups： Group A and Group B, 40 in each. The patients in Group A had injection of 2 mg/kg propofol before operatio; the patients in Group B were given 2 mg/ kg propofol combined with 1μg/kg fentanyl. An observation was made to the analgesia effect, BP, HR, R, SpO2 and the incident rate of artificial abortion complications in both groups. Results The analgesia effect of Group B were superior to those of Group A, the difference was of statistical significance （P〈0.05）;the difference of adverse effect in the 2 groups was of no statistical significance （P〉0.05）.Conclusions Propofol combined with fentanyl had good analgesia effect in artificial abortion. They were safe to patients in painless artificial abortion , and can lessen uterine contraction pain after the operation effectively without affecting conscious quality in performance and effective, worthy of wide application in primary hospitals.

关 键 词：丙泊酚 芬太尼 无痛人工流产术 

分 类 号：R1[医药卫生—公共卫生与预防医学]