颈动脉通路输注异丙酚全身麻醉施行腹部手术的临床观察  

Clinieal effect on abdominal operation by general anesthesia of propofol continuous infusion via common carotid aTtery

作　　者：陆立[1] 谭振刚[1] 郝志强[1] 栾小丹[1] 周良[1] 王禹[1] 胡世国[1] 盖成林[1] 冉德春[1] 艾长良[1] 潘阳[1] 肖艳玲[1] 苏芳[1] 孙正清[1] 陈卫民[2] 郑晓春[2] 

机构地区：[1]解放军第230医院普通外科、麻醉科,丹东118000 [2]中国医科大学盛京医院麻醉科,110001

出　　处：《丹东医药》2008年第2期4-7,共4页

摘　　要：目的评价颈动脉通路输注异丙酚全身麻醉施行腹部肿瘤手术的临床效果。方法对2006年1月至12月40例腹部肿瘤手术病人随机分为经颈动脉（IC）和经外周静脉（IV）输注异丙酚两组，对比术中麻醉效果、术后恢复和随访情况。结果两组都无与麻醉有关的并发症和死亡，麻醉效果基本相同，但IC组起效快，术中异丙酚维持量明显低于IV组，手术结束后清醒迅速，术后观察和平均随访5月未发现与麻醉有关的并发症。结论经颈动脉通路持续输注异丙酚全身麻醉用于腹部肿瘤手术效果满意，具有起效快、麻醉药用量小、术后苏醒迅速等特点，适用于腹部大手术和战伤的救治。Objective To evaluate the clinical effect on abdominal operation by general allesthesia with propofol continuous infusion via common carotid artery. Method From January 2006 to December 2006, a total of 40 patients suffering abdominal tomour were accrued for alis trial. They were randomly divided into two groups： to receive propofol via common carotid artery （IC group, n=20） or median cubitsl vein （IV group, n= 20） . The dose of propefol used, hemodyTlanlics of patients and the speed of analepsial were obseNed carefully in the two groups. The other data of the effects of aJlesthesia and restoration were collected prospectively, with complete follow-up for at least 6 months. Results There were no complications and death due to anesthesia. There was no difference in effect of allesthesia between the two groups. Anesthesia with propofol continuous infusion via common carotid artery was well tolerated without adverse effects on the eomse of the operation. Patients of IC group experienced fewer dose of propefol （P〈0.05） , and recovery of spontaneously breathing and consciousness were more quickly than that in group IV （P〈0.01） . The dose of propofol used in IC group and IV peup were 2.57±0.67mg·kg^-1·h^-1 and 5.72±1.37mg·kg^-1 ·h^-1 respectively during the operation. The mean （±SD） follw-up period was 5 （±2） months. No statistical difference was observed between the two groups. Conclusion General anesthesia with propofol continuous infusion via common carotid artery is safe and effective for major abdominal tomom resection or trauma, with quicker taking effect, lower dose, and postoperative quicker reviveseence.

关 键 词：麻醉学 颈动脉 腹部手术 

分 类 号：R614.2[医药卫生—麻醉学] R730.53[医药卫生—外科学]