痰热清注射液辅助治疗重症毛细支气管炎疗效观察  

The effect observation of Tanreqing injection in treating severe bronchiolitis

作　　者：刘敏[1] 李维新 刘玉田[1] 

机构地区：[1]山东省莱芜市人民医院,山东莱芜271100 [2]山东省莱芜市中医院,山东莱芜271100

出　　处：《儿科药学杂志》2008年第6期47-48,共2页Journal of Pediatric Pharmacy

摘　　要：目的:观察痰热清注射液辅助治疗重症毛细支气管炎的临床疗效。方法:62例重症毛细支气管炎患儿随机分为治疗组32例和对照组30例,两组患儿均采用抗感染、止咳、吸痰、雾化等常规综合治疗。治疗组在综合治疗的基础上加用痰热清注射液0.3～0.5mL/(kg.d)静脉滴注,对照组加用利巴韦林10～15mg/(kg.d)静脉滴注,疗程均为5～7d,观察疗效。结果:治疗组总有效率93.73,对照组76.67,两组比较差异有统计学意义(χ2=4.05,P<0.05)。治疗组紫绀消失时间、喘憋消失时间、心率正常时间、哮鸣音消失时间、住院天数分别为(6.88±1.20)h、(1.56±1.12)d、(2.18±0.75)d、(5.52±1.48)d、(6.80±1.50)d,均短于对照组,差异均有统计学意义(P<0.01)。两组均未见明显不良反应。结论:痰热清注射液辅助治疗重症毛细支气管炎疗效显著、安全。Objective：To observe the clinical efficacy of Tanreqing injection in the treatment of severe bronchiolitis. Methods： Sixty-two cases of children with severe bronchiolitis were randomized into the treatment group （32 cases） and the control group（30 patients）. Both groups adopted anti-infection, cough-stopping, sputum suction, atomization inhalation and other cunventional treatment. In addition, the treatment group used Tanreqing injection, while the control group used ribavirin injection at the same time. Results：The extinction time in cyanosis, hard breathing, wheezing sound and the average time of hospitalization, were shorter than that of the control group with significant differences （P 〈 0.01 ）. No obvious adverse reaction was observed. Conclusions ：Tanreqing injection in the treatment of severe bronchiolitis is significantly effective and safe.

关 键 词：痰热清注射液 重症 毛细支气管炎 婴幼儿 

分 类 号：R725.622.1[医药卫生—儿科] R259.631[医药卫生—临床医学]