兔皮肤和骨损伤的超微结构与损伤时间推断研究  

STUDY ON THE TIMING INFERENCE OF WOUND IN RABBIT’S SKIN AND BONE

作　　者：喻林升[1] 朱金昌[1] 胡芸[1] 方周溪[2] 王琳[2] 

机构地区：[1]温州医学院病理学教研室 [2]温州医学院电镜室

出　　处：《温州医学院学报》1997年第1期16-19,共4页Journal of Wenzhou Medical College

基　　金：温州医学院科学基金

摘　　要：兔小腿皮肤和骨损伤后，经１天、４天、７天、１４天、２１天、２８天，分别用光镜及电镜进行了观察，并计算ｒａ／ｆａ和ｃｃｎ／ａｃｎ值。结果表明：①皮肤损伤后４天，纤维母细胞内浆网扩张，７天达最高峰，ｒａ／ｆａ为２３．１３％，１４天后缩小；②皮肤损伤１天，即出现肌纤维母细胞，损伤４天胞浆内出现微丝束，７天～１４天微丝束最多；③骨损伤切口细胞数在１天最多，ｃｃｎ／ａｃｎ值最高，４天和７天也较多，１４天和２１天下降，２８天仍未降至正常。这些变化规律为损伤时间推断提供新的定量指标。Experimental incised wounds were made on the skin and bone of rabbit’s legs under anesthesia using aseptic technique.After 1,4,7,14,21 and 28 dags,wounds were observed under light and electronic microscope,the ra/fa ratio and ccn/acn ratio were calculated.The results were as follows:(1)The endoplasmic reticulum of fibroblast expanded in 4 days after wounding,with the ra/fa ratio 23.13% at this time,and reduced 14 days after wounding.(2)The myofibroblasts appeared in l day after wounding.The microfilaments appeared in 4 days after wounding and reached a maximum gradually from the 7th to the 14th day.(3)The ccn/acn ratio at bone were the highest in lday after wounding,reduced from the 14th to the 21st day and did not drop to normal in 28 days after wounding.

关 键 词：皮肤损伤 骨损伤 超微结构 损伤时间 

分 类 号：R641.02[医药卫生—外科学] R683.02[医药卫生—临床医学]