中枢神经细胞瘤磁共振成像及氢质子磁共振波谱的诊断价值  

Diagnostic values of magnetic resonance imaging and proton magnetic resonance spectroscopy in central neurocytoma

作　　者：郭青[1] 徐香玖[2] 黄刚[2] 胡臣文[1] 马钦华[1] 董汉彬[1] 王建国[1] 

机构地区：[1]深圳市第五人民医院放射科,广东深圳518001 [2]甘肃省人民医院放射科,甘肃兰州730000

出　　处：《兰州大学学报（医学版）》2008年第4期69-72,76,共5页Journal of Lanzhou University（Medical Sciences）

摘　　要：目的探讨中枢神经细胞瘤（CNC）的常规磁共振成像（MRI）和氢质子磁共振波谱（^1H MRS）的表现特征和诊断价值。方法回顾性分析5例经手术病理证实的CNC进行常规MRI检查，其中4例加做多体素^1H MRS，并分析其MRI及。HMRS表现。结果5例CNC患者肿瘤特征性位于侧脑室，邻近Monra孔并累及透明隔。在T1加权成像4例呈等低不均匀信号，l例呈等高不均匀信号；T2加权成像呈等高不均匀信号；增强后肿瘤呈中度及明显不均匀强化。4例^1H MRS均表现为胆碱峰明显增高，N-乙酰门冬氨酸（NAA）峰下降，胆碱／肌苷比值升高，NAA／肌苷比值降低。结论20-40岁的患者发生于侧脑室透明隔处邻近Monra孔的肿瘤，结合其MRI及^1H MRS表现特征应考虑到CNC诊断。Objective To investigate the manifestation features and diagnostic values of magnetic resonance imaging（MRI） and proton magnetic resonance spectroscopy（^1H-MRS） in central neurocytoma（CNC）. Methods 5 cases of CNC confirmed pathologically were examined with routine MRI, out of them, 4 cases were examined with multivoxel MR proton spectroscopy. Results All of CNC masses in our study were typically located in the ventricles near the foramen of Monra with a characteristic attachment to the septum pellucidum. 4 cases were inhomogeneously isointense to hypointense and 1 case was mixed isointense to hyperintense on TIWI. 5 cases were inhomogeneously isointense to hyperintense on T2WI. Contrast TIWI images revealed inhomogeneously enhancement ranging from moderate to remarkable. The ^1H MRS images of 4 cases displayed increased choline resonance, reduced N-acetyl aspartate（NAA） resonance. The ratio of choline/creatinine was increased and NAA/creatinine decreased. Conclusion Central neurocytoma should be considered with the characteristic manifestations of MRI and ^1H MRS when a mass is located in the ventricles near the foramen of Monra with a characteristic attachment to the septum pellucidum in young men aged from 20 to 40.

关 键 词：中枢神经细胞瘤 磁共振成像 磁共振波谱 

分 类 号：R445.2[医药卫生—影像医学与核医学]