2006年青海省兴海县大骨节病调查报告  

Investigation on Kashin-Beck disease in Xinghai County, Qinghai Province in 2006

作　　者：李强[1] 赵志军[1] 

机构地区：[1]青海省地方病预防控制所微量元素病预防控制科,西宁811602

出　　处：《中国地方病学杂志》2008年第6期681-682,共2页Chinese Jouranl of Endemiology

基　　金：卫生部疾控司委托资助项目（2006）

摘　　要：目的通过对青海省兴海县大骨节病新发病区调查，了解大骨节病病区分布范围、流行强度和流行趋势，为大骨节病防治研究提供依据。方法按全国大骨节病监测方案要求，对兴海县唐乃亥乡、子科滩镇、桑当乡及曲什安乡共6个村的7～13岁儿童进行流行病学调查、临床检查及X线拍片，并采集发样、粮样、土样、水样，用2、3-二氨基萘荧光法进行含硒量测定。结果在4个调查点的6个村共临床检查7～13岁少年儿童373人，检出大骨节病45例，检出率为12．06％。X线拍片347人，X线阳性75例，阳性检出率为21．61％。子科滩镇泉曲村含硒量最低，发硒为（77．70±42．04）μg／kg，粮硒为（7．44±6．93）μg／kg；曲什安乡才乃亥村含硒量最高，发硒为（103．88±58．57）μg／kg，粮硒为（29．58±24．11）μg/kg。结论兴海县4个调查点为大骨节病新病区。调查点大骨节病病情严重，致病因子活跃。Objective By investigating newly diagnosed Kashin-beck disease, to understand distribution range, epidemic intensity and prevalence trend of Kashin-Beck disease（KBD） in Xinghai County. Method According to monitoring method on national KBD, we carried on epidemical investigation, clinical examination and X-ray photograph on school children aged 7 - 13 years in 6 villages from 4 towns in Xinghai County, and hair, grain, water and soil were sampled to detect selenium content using naphthalene fluorescence. Result Three hundred and seventy-three school children aged 7 - 13 years underwent the clinical examination, the prevalence rate was 12.06% （45/373）; 347 school children were went on X-ray, the detection rate of X-ray was 21.61% （75/347）. The selenium content was the lowest in Quanqu Village, Ziketan Town, which were（77.70 ± 42.04）, （7.44 ±6.93）μg/kg respectively; the selenium content was highest in Cainaihai Village, Qushian Town, which were （103.88±58.57）, （29.58 ± 24.11 ）μg/kg respectively; level of in internal and external environment in 4 KBD region were all low. Conclusion These four region are new KBD region. The prevalence state of KBD is serious, pathogenetic factor of Kashin-Beck disease is very active.

关 键 词：大骨节病 流行病学 X线 

分 类 号：R686[医药卫生—骨科学]