生物医用纳米羟基磷灰石的性质及其制备  

Characteristics and preparation of nanometer hydroxyapatite in medical science

作　　者：李颖华[1] 曹丽云[1] 黄剑锋[1,2] 曾燮榕[2] 

机构地区：[1]陕西科技大学材料科学与工程学院,陕西省西安市710021 [2]深圳大学深圳市特种功能材料重点实验室,广东省深圳市518060

出　　处：《中国组织工程研究与临床康复》2008年第41期8143-8146,共4页Journal of Clinical Rehabilitative Tissue Engineering Research

基　　金：陕西省教育厅自然科学专项基金(项目编号:08JK220)~~

摘　　要：羟基磷灰石是动物和人体骨骼的主要无机矿物成分,当羟基磷灰石的尺寸达到纳米级时将表现出一系列的独特性能。纳米羟基磷灰石既有纳米材料的特性,又有良好的生物相容性,在生物医学领域具有非常广阔的应用前景。文章介绍了纳米羟基磷灰石的历史发展、结构特性及制备方法。对纳米羟基磷灰石的发展前景进行了展望。指出:纳米羟基磷灰石的大批量工业化低成本制备尚存在一定困难,工业化设备的研发将是下一步研究的重点。此外,通过复合技术和涂层技术有望解决医用纳米羟基磷灰石材料的脆性问题。Hydroxyapatite is the main inorganic mineral component in animals and human bone, and nanometer hydroxyapatite may show a series of specific characteristics. Nanometer hydroxyapatite with the characteristics of nanometer materials and good biocompatibility has a wide application in biomedical field. The development process, crystal structure and processing methods of nanometer hydroxyapatite are reviewed. Also the development direction of nanometer hydroxyapatite is prospected. It is pointed out that the main problem in producing nanometer hydroxyapatite in a large scale with low-cost in industrial preparation is difficult to solve. The exploitation of industrial equipments for the preparation of nanometer hydroxyapatite will be the next research focus. In addition, the brittleness problem of nanometer hydroxyapatite in biomedical applications can be solved through composite technologies and coating techniques.

关 键 词：纳米 羟基磷灰石 生物医学材料 

分 类 号：R318[医药卫生—生物医学工程]