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作 者:崔向丽[1] 李明[1] 高颖昌[1] 陈丽[1] 赵志刚[1]
机构地区:[1]首都医科大学附属北京天坛医院药剂科,北京市100050
出 处:《中国医院用药评价与分析》2008年第11期833-836,共4页Evaluation and Analysis of Drug-use in Hospitals of China
摘 要:目的:评价我院门诊患者抗抑郁药的应用现状及趋势,为临床合理用药提供参考。方法:对我院2005~2007年门诊患者使用抗抑郁药的种类、销售金额、用药频度(DDDs)等进行统计、分析。结果:抗抑郁药的处方数、购药金额及DDDs等逐年增长,5-羟色胺再摄取抑制剂(SSRI)是临床治疗抑郁症的首选药物,3年处方数比例都在80%以上。帕罗西汀、西酞普兰、氟西汀、舍曲林等SSRI在3年中都是应用最多的药物。结论:本院的抗抑郁药应用基本合理。SSRI类抗抑郁药的应用3年中占主导地位,三环类抗抑郁药(TCAs)应用较少。OBJECTIVE: To evaluate the utilization status and trends of antidepressive drugs in outpatients of our hospital from 2005 to 2007 and provide a reference for clinical rational use of drugs. METHODS: The types, consumption sum and DDDs of anti-depressants in our hospital from 2003 to 2005 were analyzed statistically. RESULTS: The prescription number, consumption sum, and DDDs of antidepressants increased year by year over the three years. Selective serotonin reuptake inhibitors (SSRIs) were the choice drugs for depression, representing more than 80% over the 3 years. Paroxetine, citalopram, fluoxetine and sertraline remained to be the dominant kinds among all the SSRIs over the 3 years. CONCLUSION: The use of antidepressive drugs in our hospital was rational on the whole. SSRIs have been dominating the list among all the antidepressive drugs in clinic over the 3 years, while the proportion of tricyclic antidepressant (TCAs) was less.
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