K系维生素中间体β-甲基萘醌的合成工艺研究  

Synthesis of k-series Vitamins intermediates 2-Methyl-1,4-naphthoquinone

作　　者：王凤军[1] 靳会杰[1] 刘国际[1] 雒廷亮[1] 

机构地区：[1]郑州大学化学工程学院,郑州450002

出　　处：《化工中间体》2008年第12期33-36,共4页

摘　　要：本实验研究了一种新颖且环境友好的β-甲基萘醌的合成方法。该方法以冰醋酸为溶剂,OP-10为乳化剂,过氧化氢作为氧化剂,氧化β-甲基萘制取β-甲基萘醌。分别考察了反应温度、反应时间、β-甲基萘与冰醋酸摩尔比等因素对β-甲基萘醌转化率和收率的影响。从而得到较优反应条件为:反应温度100℃;反应时间4h;n(β-甲基萘):n(冰醋酸)为1:16;n(β-甲基萘):n(H2O2)为1:11;OP-10用量0.05ml/g(β-MN)。在此条件下,β-甲基萘醌的转化率可达96%,收率可达52%。This paper study a novel and environmentally synthesis route for β- methylnaphthoquinone. Synthesis of β- methylnaphthoquinone with OP-10 as the emulsifier in the acetic-H2O2 system by oxidation of β- methylnaphthalene was researched. The effects of reaction temperature, reaction time, molar ratio of β-methylnaphthalene to glacial acetic acid and molar ratio of β-methylnaphthalene to Hydrogen peroxide on β- methylnaphthoquinone conversion and yield were investigated.The optimal reaction conditions were that reaction temperature was 100 ℃, reaction time 4h, molar ratio of β -methylnaphthalene to acetic acid 1：16 ,molar ratio of β - methylnaphthalene to Hydrogen peroxide 1：11 and OP-10 0.05ml/g（β-MN）. In these conditions, β- methylnaphthalene conversion was 96%, the yield of β-methyl-naphthoquinone was above 52% .

关 键 词：Β-甲基萘 Β-甲基萘醌 过氧化氢 氧化 OP-10 

分 类 号：TQ244[化学工程—有机化工]