乙二醇苯醚的相转移催化合成研究  

Study on Synthesis of Glycol Phenyl Ether by Phase Transfer Catalyst

作　　者：孙冬兵 王树清[2] 高崇[2] 

机构地区：[1]南通惠康国际企业有限公司,南通226009 [2]南通大学化学化工学院,南通226007

出　　处：《精细石油化工进展》2008年第11期24-27,共4页Advances in Fine Petrochemicals

摘　　要：在四丁基溴化铵相转移催化剂存在下,以苯酚、2-氯乙醇为原料合成乙二醇苯醚,分别研究了反应温度、反应时间、原料配比、催化剂用量等对合成反应的影响,试验确定合成乙二醇苯醚的最佳工艺条件如下:0.1 mol 苯酚,n(苯酚):n(2-氯乙醇):n(氢氧化钠)=1:1.3:1.05、反应温度95℃、反应5 h、溶剂苯用量为30 mL,催化剂用量为0.75 g,在此条件下,乙二醇苯醚的收率可达88.76%,乙二醇苯醚纯度98.5%。Glycol phenyl ether was synthesized from phenol and 2 - chloroethanol in the presence of tetrabutylammonium bromide as phase transfer catalyst. The effects of reaction conditions such as reaction temperature, reaction time, ratio of reaction material, dosage of catalyst etc. on the reaction were examined. The optimum reaction conditions were as follows： the reaction temperature 95 ℃ ,reaction time 5 hours,n（phenol） ： n （2 - chloroethanol） = 0.1 ： 0.13, n （ phenol ） ： n （ sodium hydroxide） = 0.1 ： 0.105, volume of solvent 30 mL, the dosage of phase transfer catalyst 0.75 g （ based on 0. 1 tool phenol）. The yield and purity of glycol phenyl ether could reach 88.76% and 98.5% respectively.

关 键 词：乙二醇苯醚 2-氯乙醇 苯酚 相转移催化 

分 类 号：TQ243[化学工程—有机化工]