2,6-二(2′-芳基-3′-N-乙酰基-1′,3′,4′-噁二唑啉基)吡啶的合成与表征  

Synthesis and characterization of 2,6-bis(3′-N-acetyl2′-phenyl-1′,3′,4′-oxadiazoline)pyridine

作　　者：陈桐滨[1] 张熊禄[2] 范小林[2] 

机构地区：[1]韩山师范学院化学系,广东潮州521041 [2]赣南师范学院江西省有机药物化学重点实验室,江西赣州341000

出　　处：《化学试剂》2008年第12期919-920,923,共3页Chemical Reagents

基　　金：国家自然科学基金资助项目(50568001);江西省教育厅科技项目(2007291)

摘　　要：2,6-吡啶二甲酸经酯化、肼解首先合成2,6-吡啶二酰肼,再跟芳香醛缩合得到酰腙,进而用乙酸酐脱水闭环,合成7个含吡啶环的双噁二唑啉衍生物,其结构用1HNMR、FT-IR、MS进行了验证并对其波谱学特征予以讨论。2, 6-Pyridine di-acylhyrazines were prepared through esterification and hydrazinolysis of pyridine 2, 6-dicarboxylic acid. Condensation of 2,6-pyridine di-acylhyrazines with aromatic aldehydes yielded the corresponding hydrazones, which were cyclodehydrated with acetic anhydride to form the title compounds. Their molecule structures were characterized by ^1HNMR, FT-IR and MS. The typical spectral properties of these compounds were discussed.

关 键 词：吡啶环 1 3 4-噁二唑啉 合成 

分 类 号：O626.24[理学—有机化学]