3种方案干预治疗新生儿黄疸的成本-效果分析  

Cost-Effectiveness Analysis of Three Therapeutic Schemes for Neonatal Jaundice

作　　者：吴曙粤[1] 王艳宁[1] 王利民[1] 黄仕孙[1] 高桂娥[1] 

机构地区：[1]南宁市第一人民医院,南宁市530022

出　　处：《中国药房》2008年第35期2721-2723,共3页China Pharmacy

基　　金：南宁市科学研究与技术开发计划项目(20040246C)

摘　　要：目的:评价3种方案干预治疗新生儿黄疸的经济学效果。方法:120例足月正常新生儿随机分为3组,分别给予退黄外洗液药浴(A组)、口服苯巴比妥+加味茵陈汤(B组)、口服苯巴比妥(C组)治疗6d后评价疗效及不良反应,并进行成本-效果分析。结果:A、B、C组总有效率分别为95.0%、92.5%、82.5%,总成本分别为259.20、131.88、127.38元,成本-效果比分别为272.84、142.57、154.40,A、B组增量成本-效果比分别为1054.56、45.00。A组黄疸出现时间较B、C组推迟约4h,且无不良反应。结论:B组方案在成本-效果比较中较优,但综合治疗比较中,A组方案较优且便于使用。OBJECTIVE： To evaluate the cost - effectiveness of three therapeutic schemes in the treatments of neonatal jaundice. METHODS： 120 healthy full- term infants were randomly assigned to Group A applied with Jaundice- abating Chinese Herbal Lotion for medicated bath, Group B treated with Phenobarbital po plus Jiawei Yinchen Decoction, and Group C with Phenobarbital po After 6-day treatment, the curative efficacy and adverse drug reactions were evaluated and the cost-effectiveness analyses of the three groups were conducted. RESULTS： The effective rates of A , B and C groups were 95.0%, 92.5% and 82.5% respectively; the total costs were 259.20, 131.88 and 127.38 Yuan respectively, and the cost- effective ratios were 272.84, 142.57, and 154.40 respectively. As compared with Group C, the incremental cost- effective ratios for A and B groups were 1 054.56 and 45.00. Furthermore, the Jaundice appeared 4 hours later in Group A than in B and C groups and there was no adverse reaction in Group A. CONCLUSION： Group B is optimal in cost- effectiveness; however, Group A is superior and easy to use if taking all factors into consideration.

关 键 词：新生儿黄疸 退黄外洗液 成本-效果分析 

分 类 号：R956[医药卫生—药学] R985