我院258例药品不良反应报告分析  

Adverse Drug Reactions in Our Hospital:Analysis of 258 Cases

作　　者：冯新[1] 章红[1] 李青[1] 

机构地区：[1]江西省人民医院药剂科,南昌市330006

出　　处：《中国药房》2008年第35期2783-2784,共2页China Pharmacy

摘　　要：目的:了解我院药品不良反应(ADR)发生的特点及规律。方法:对我院2006年6月～2008年6月收集到的258例ADR报告,分别从患者性别、年龄、药品种类、临床表现、给药途径、药物剂型等方面进行统计、分析。结果:258例ADR中,以抗微生物类药物引起ADR最多(占64.34%);在临床表现方面以皮肤及其附件损害占多数(占45.74%);静脉注射是引起ADR的主要给药途径(占77.91%)。结论:开展和加强临床ADR监测与报告工作是提高用药安全性的重要内容。OBJECTIVE： To investigate the characteristics and general pattern of the adverse drug reactions （ADR） occurred in our hospital. METHODS： A total of 258 ADR cases collected from June 2006 to June 2008 were analyzed statistically in respect of patients＇ age and sex, drug variety, clinical manifestations, routes of administraiton and dosage forms etc. RESULTS： Of the total 258 ADR cases, the majority（64.34% ） were induced by antimicrobial drugs; 45.74% presented with lesions of skin and its appendants, and 77.91% were induced by intravenous way. CONCLUSION： To develop and strengthen ADR monitoring and reporting should be regarded as the key to enhance medication safety.

关 键 词：药品不良反应 分析 合理用药 

分 类 号：R969.3[医药卫生—药理学]