喹啉铜原药高效液相色谱分析方法  

Analytical Method for the Determination of Oxine-copper by HPLC

作　　者：周梦春[1,2] 蔡磊明[1] 赵凌菲[1] 贾福艳[1] 胡耐冬 舒耀皋[1,2] 魏海燕[1,2] 王润欢[1,2] 

机构地区：[1]沈阳化工研究院安评中心,沈阳110021 [2]新疆农业大学,乌鲁木齐830052

出　　处：《农药》2008年第12期891-892,共2页Agrochemicals

摘　　要：建立了喹啉铜原药的超声波辅助溶剂提取-反相离子对高效液相色谱法的分析方法。该方法使用XBridgeC18色谱柱和可变波长紫外检测器,并以20mmol/L十二烷基硫酸钠水相体系-乙腈(体积比为60∶40)作流动相;流速为0.6mL/min;检测波长为250nm;保留时间为8.52min;方法的线性相关系数为0.9998,样品平均回收率为99.3%,变异系数在0.05%～0.13%之间,对喹啉铜原药的最低检出限为0.02mg/L。The method was established to analysis the oxine-copper with ion pair of antiphase HPLC and Ultrasonicassisted solvent extraction methods. This methods mainly uses XBridge C18 column and UV detector by using waters phase of 20 mmol/L sodium dodecyl sulfate solution/acetonitrile （60：40, by vol） as mobile phase with 0.6 mL/min flow ratio and UV detection at 250 nm. The residue time was 8.52 minute. The linear coorelation of this method was 0.9998. The average recovery rate was 99.3%. The coefficient of variation was 0.05 to 0.13%. The detection limit of method was 0.02 mg/L.

关 键 词：喹啉铜原药 定量分析 反相离子对 高效液相色谱 

分 类 号：TQ455.4[化学工程—农药化工]