15例孤立性肿瘤的氩氦刀治疗  

Percutaneous cryoablation of unifocal tumor under ultrasonic guidance

作　　者：李建雄[1] 焦顺昌[1] 杨俊兰[1] 李方[1] 戴广海[1] 赵宏[1] 白利[1] 

机构地区：[1]解放军总医院肿瘤内科,北京100853

出　　处：《军医进修学院学报》2008年第6期485-486,共2页Academic Journal of Pla Postgraduate Medical School

基　　金：全军十一五重大课题(06G106);面上课题(06MA295)

摘　　要：目的:探讨氩氦刀治疗孤立性肿瘤的疗效及安全性。方法:15例单个病灶肿瘤患者在超声引导下进行氩氦刀治疗。结果:13例患者的肿瘤病灶被氩氦刀所形成的冰球100%覆盖,其余两例患者肿瘤病灶冰球的覆盖率也在90%以上。完全缓解13例,部分缓解2例,有效率达100%,无疾病进展生存期为8个月,其中1例无疾病进展生存期达15个月。结论:氩氦刀治疗孤立的肿瘤病灶安全有效,肿瘤的大小和位置是影响治疗效果的决定性因素。Objective： To observe the feasibility and safety of cryoablation of unifocal tumor for nonsurgical candidates.Methods： The procedure was performed after achievement of local anesthesia for 15 tumors in 15 patients（13 male and 2 female patients）.Results： The cryoprobe was successfully placed under ultrasound guidance in the tumor in 15（100%） of 15 patients.15 had two freeze cycles consisting of a 15-or 20-minute freeze and a 2-minute thaw.Tumors of 13 patients were thoroughly covered by ice balls.The mean greatest dimension of breast cancer was 8 cm,and 90% of area was covered by ice balls.Median Time-to-progression is eight months.Conclusion： Percutaneous cryoablation therapy for unifocal tumor under ultrasonic guidance is feasible and minimally invasive,with satisfactory local control.Tumor magnitude and location were dependent determinants of ice ball coverage.

关 键 词：氩氦靶向治疗 肿瘤 超声检查 介入性 

分 类 号：R246.5[医药卫生—针灸推拿学]