人工肝支持系统救治妊娠重症肝炎临床研究  

Clinical efficacy of artificial liver supporting system in treatment of pregnancy complicated severe hepatitis

作　　者：林玉英[1] 曾金秋[1] 邱荣仙[1] 何雄志[1] 唐淑芬[1] 

机构地区：[1]莆田学院附属医院感染性疾病科,福建莆田351100

出　　处：《右江民族医学院学报》2008年第6期933-934,共2页Journal of Youjiang Medical University for Nationalities

基　　金：莆田市科技局立项;编号:2004S12

摘　　要：目的探讨人工肝支持系统(ALSS)救治妊娠重症肝炎的临床效果。方法将31例妊娠重症肝炎患者分为两组:ALSS治疗的13例为治疗组,无ALSS治疗的18例为对照组,比较两组总胆红素(TBIL)、白蛋白(ALB)、凝血酶原活动度(PTA)水平和分娩出血量、产妇及围生儿预后情况。结果两组治疗后产前TBIL、ALB、PTA水平比较差异有高度显著性(P均<0.01)。治疗组治疗前后TBIL、ALB、PTA水平比较差异有高度显著性(P均<0.01)。治疗组分娩出血量、产妇病死率明显低于对照组(P均<0.01)。结论ALSS抢救妊娠重症肝炎有效,且能较好地降低产妇及围生儿病死率。Objective To discuss the clinical efficacy of artificial liver supporting system （ALSS） in treatment of pregnancy complicated severe hepatitis. Methods Thirty- one pregnant women complicated severe hepatitis were divided into two groups： 13 cases in the therapeutic group receiving ALSS treatment, 18 cases in the control group without ALSS treatment. Compared of serum total bilirubin （TBIL）, albumin （ALB）, prothrombin activities （PTA）, the volume of intrapartum bleeding, outcomes of parturients and perinataI infants between therapeutic group and control group. Results Before labor and after treatment, there were significant differences in TBIL, ALB and PTA between the two groups （all P values 〈0.01）. There were significant differences in TBIL, ALB and PTA for therapeutic group before and after treatment （all P values〈0.01）. The volume of intrapartum bleeding and parturient mortality for therapeutic group were lower than those for the control group （all P values〈 0. 01）. Conclusion ALSS is effective for rescuing pregnancy complicated severe hepatitis, and can decrease the mortality of parturients and perinatal infants.

关 键 词：妊娠 肝炎 肝 人工 

分 类 号：R714.25[医药卫生—妇产科学] R512.6[医药卫生—临床医学]