药用植物松塔的化学成分研究  

Chemical Constituents from Pine Cone of Pinus Armandii Franch.

作　　者：周明波[1] 刘光明[1] 吕永俊[1] 方建全[1] 张桢[1] 

机构地区：[1]大理学院药学院,云南大理671000

出　　处：《大理学院学报（综合版）》2008年第10期1-4,共4页Journal of Dali University

基　　金：国家自然科学基金资助项目(30860365)

摘　　要：目的:对松科(Pinaceae)华山松(Pinus armandii Franch.)松塔的化学成分进行研究,以期寻找活性成分。方法:松塔的乙醇冷浸提取浸膏,依次用石油醚、氯仿、乙酸乙酯和正丁醇萃取,分别得到石油醚、氯仿、乙酸乙酯和正丁醇的萃取物。氯仿和正丁醇萃取物用正、反相色谱法,MCI、Pharmadex LH-20凝胶柱色谱法和HPLC法分离,分离得到6个化合物。结果:根据理化性质和利用NMR、ESI-MS等波谱技术鉴定化合物结构,鉴定了其中的4个化合物:异海松烷(Ⅰ);Dehydroabietic acid(Ⅱ);β-谷甾醇(Ⅲ);β-胡萝卜苷(Ⅳ)。结论:其中化合物Ⅰ～Ⅱ为首次从该种植物中分离得到。Objective： To study the chemical constituents from the pine cone of P. armandii Franch, aiming at searching for bioactive natural products. Methods： Column chromatography techniques were used for separation and purification of the compounds and extensive spectral analyses spectrum were employed for structural elucidation. Results： Four compounds were isolated from the pine cone of P. armandii Franch. , and their structures were identified by means of spectroscopic analysis as： isopimaric （Ⅰ）, Dehydroabietic acid （Ⅱ）, β-sitosterol （Ⅲ） and daucosterol （Ⅳ）. Conclusion： Compounds Ⅰ-Ⅱ were isolated from this plant for the first time.

关 键 词：华山松 松塔 化学成分 二萜 

分 类 号：Q946[生物学—植物学]