小儿氨酚烷胺栓剂基质的选择  

Matrix Screen of Paracetamol and Amantadine Hydrochloride Suppository for Children

作　　者：李雯[1] 罗帅[1] 黄波[1] 缪菊莲[1] 

机构地区：[1]大理学院药学院,云南大理671000

出　　处：《大理学院学报（综合版）》2008年第10期8-9,共2页Journal of Dali University

摘　　要：目的:对新研制的小儿氨酚烷胺栓剂进行基质的筛选,选出比较适宜的基质。方法:通过检查基质重量差异、融变时限、外观、硬度等指标,优选较好的基质。结果:小儿氨酚烷胺选取脂溶性基质时,外观及融变时限、重量差异、硬度均比水溶性基质好。结论:小儿氨酚烷胺的基质选择脂溶性基质较好。Objective： To screen the matrix of the newly developed Paracetamol and Amantadine Hydrochloride for children in order to get a more appropriate matrix. Methods： Good matrix was screened by examining the weight difference, melting time, appearance, hardness, etc. Results： For children＇s Paracetamol and Amantadine Hydrochloride, fat-soluble matrix was better concerning the melting time, the weight difference and hardness. Conclusion： Fat-soluble matrix was better in screening Paracetamol and Amantadine Hydrochloride for children.

关 键 词：小儿氨酚烷胺 栓剂 基质 筛选 融变时限 

分 类 号：R944.2[医药卫生—药剂学]