补肾活血法干预管性不孕生殖道感染所致免疫失衡的观察  

Clinical observation on tubal factor infertility with the immunologic unbalance by gential tract infections by Bushen Huoxue Method

作　　者：王慧民[1] 梁瑞宁[2] 胡丽莎[1] 

机构地区：[1]江西省妇幼保健院 [2]江西中医学院附属医院,南昌330006

出　　处：《江西医药》2008年第11期1133-1136,共4页Jiangxi Medical Journal

基　　金：江西省卫生厅资助项目(No.20045039)

摘　　要：目的研究输卵管介入再通术后补肾活血法对输卵管不孕生殖道感染所致免疫失衡的干预作用。方法两组均于月经干净后3～7d内行输卵管介入术,并于下个月经周期常规行宫腔输卵管通液术1次,注入香丹注射液40ml。治疗组于月经周期第5d开始加服补肾活血剂,每天1剂,每月连服14剂。3个月为1个疗程,共观察4个疗程。结果两组治疗后卵泡发育情况、子宫内膜厚度、排卵前期血清雌二醇(E2)值与本组治疗前比较,差异均有显著性(P<0.05,P<0.01),且治疗组优于对照组(P<0.05,P<0.01)。治疗组免疫抗体转阴率、妊娠率高于对照组,两者比较差异有显著性(P<0.05)。结论输卵管介入术后通过补肾活血法能明显改善输卵管阻塞性不孕患者生殖道感染所致免疫失衡状况,从而提高妊娠率。Objective To study the effect on the immunologic unbalance by gential tract cniamydia trachomatis and ureplasma urealyticum infections by Bushen Huoxue method after the therapy of fallopian tube recanalization （VFR）.blethods To all the patients, salpingostomy was performed 3 to 7 days after menstruation and hydrotubation with Xiangdan Injection （XI）was applied once in the next menstrual cycle.Bushen Huoxue Decoction（BHD）was administrated additionally to patients in the treated group, 1 dose every day starting from the 5th day of menstrual cycle for 14 days.Three months＇treatment was taken as one therapeutic course and the observation lasted for 4 courses.Results The condition of follicular development, thickness of endometriumand level of serum estradiol in the preovulatory phase after treatment were all significantly increased in the two groups （P〈0.05 and P〈0.01）;but the improvement in the treated group was significantly superior to that inthe control group,showing significant difference.Moreover,the decreased degree of the antireproductive antibodies positive rates,the pregnancy rate were also higher in the former than in the latter（P〈0.05）.Conclusion Bushen Huoxue Method after FTR has the effect on improving the condition with immunologic unbalance, and elevating the pregnancy rate in tubal factor infertility women.

关 键 词：输卵管阻塞性不孕 生殖道感染 抗生殖抗体输卵管介入术 补肾活血法 

分 类 号：R711.76[医药卫生—妇产科学]