合并2型糖尿病老年冠心病患者冠状动脉病变程度的研究  

Study on the coronary angiographic characteristics among elder patients with coronary heart disease complicated with diabetes mellitus

作　　者：罗亚玮[1] 陈方[1] 张维东[1] 张晓玲[1] 高阅春[1] 李峥[1] 吴长燕[1] 何继强[1] 李宇[1] 

机构地区：[1]首都医科大学附属安贞医院心内科,北京市100029

出　　处：《中华实用诊断与治疗杂志》2008年第12期910-912,共3页Journal of Chinese Practical Diagnosis and Therapy

摘　　要：目的:探讨合并2型糖尿病老年冠心病患者的临床特点和冠状动脉病变特征。方法:回顾性分析本院1 102例老年冠心病患者的临床资料及冠状动脉造影结果。结果:与不合并糖尿病患者比较,合并2型糖尿病肥胖和高血压比例、最高收缩压、最高舒张压、三酰甘油、血糖、尿酸均显著增高,高密度脂蛋白胆固醇酯水平显著降低,平均冠状动脉病变处数、长病变、分叉病变和多支病变发生率显著增高(P<0.05),冠状动脉病变更严重、更弥漫,平均置入支架数目多(P<0.01),平均支架直径小而长(P<0.05)。结论:合并糖尿病的老年冠心病患者代谢异常更显著,冠状动脉硬化范围更广、程度更重,多支病变、弥漫病变常见,需要介入干预的比例高。Objective To study the coronary artery pathological changes and clinical characteristics of elder patients with coronary heart disease complicated with diabetes mellitus. Methods One thousand one hundred and two elder patients with coronary heart disease were divided into the group complicated with diabetes mellitus （DM group） and group not complicated with diabetes mellitus （No-DM）. The clinical and coronary angiographic data were analyzed between two groups. Results In DM group, the ratio of hypertension and obesity was much higher（P〈0.05）, serum triglyceride increased and high density lipoprotein-cholesterol decreased （P 〈 0. 05）, blood glucose and uric acid were significantly higher （P〈0.05）, two- and three- vessel diseases of coronary artery, long stenotic lesion and bifurcation lesion were more prevalent than those in the No-DM group （P〈0.05）. The patients in DM group should be implanted more and smaller and longer stents than the No-DM group. Conclusion The coronary heart disease elder patients with diabetes mellitus have more multi-vessel lesions and much greater extent and much severe coronary vessel involvement. More coronary heart disease elder patients with diabetes mellitus need percutaneous coronary intervention.

关 键 词：冠心病 糖尿病 冠状动脉造影 

分 类 号：R541.4[医药卫生—心血管疾病]