硝酸甘油缓解性胸痛对冠心病诊断的意义  

Changes in the Numeric Descriptive Scale for Pain after Sublingual Nitroglycerin do not Predict Cardiac Etiology of Chest Pain

作　　者：赵晓梅[1] 李敬霞[1] 罗谊[1] 张亚敏[1] 王海昌[1] 胡涛[1] 

机构地区：[1]第四军医大学西京医院心内科,西安710032

出　　处：《医学研究杂志》2008年第12期93-94,共2页Journal of Medical Research

摘　　要：目的探讨胸痛可被舌下含服硝酸甘油缓解在冠心病诊断中的价值。方法以2006年8月～2008年4月期间由于胸痛到第四军医大学西京医院就诊入院的患者689例进行前瞻性研究,将其冠状动脉造影结果与胸痛可被硝酸甘油缓解的结果进行对比分析。结果689例患者中,共有282例(41%)患者的胸痛可被硝酸甘油缓解。在确诊为冠心病的患者364例中有39%患者(142例)的胸痛可被硝酸甘油缓解,而在非冠心病病因引起胸痛的患者325例中有43%患者(140例)的胸痛可被硝酸甘油缓解,两者无显著性差异(P>0.5)。结论胸痛可被舌下含服硝酸甘油缓解并不有助于诊断冠心病。Objective To determine whether the change in numeric descriptive scale for pain after sublingual nitroglycerin use can predict cardiac etiology of chest pain. Methods From Aug 2006 toApr 2008, 689 patients presented to the Xijing hospital for chest pain were prospectively studvied. The findings of the response of chest pain to sublingual nitroglycerin and coronary angiography（CAG） received sublingual nitroglycerin were retrospectively analyzed. Results In 689 patients,282（41% ）patients had significant or complete reduction in pain after sublingual nitroglycerin use. There was no significant diference in response to sublingual nitroglycerin between patients with and without a diagnosis of cardiac chest pain（P 〉 0.5）. Conclusion The response of chest pain to sublingual nitroglycerin is not a reliable indicator of a cardiac etiology of chest pain.

关 键 词：冠心病 诊断 硝酸甘油 胸痛 

分 类 号：R446[医药卫生—诊断学] R541.4[医药卫生—临床医学]