孕妇血清风疹病毒抗体IgM检测的临床意义  

The clinical value of detecting RV-IgM antibody in sera of pregnant women

作　　者：夏秀玲 

机构地区：[1]山东省临清市妇幼保健院检验科,252600

出　　处：《中国实用医药》2008年第36期19-20,共2页China Practical Medicine

摘　　要：目的探讨孕妇血清风疹病毒IgM抗体检测的临床价值。方法采用酶联免疫吸附法(ELISA)检测230例孕妇血清中的风疹病毒特异性抗体IgM。结果230例中IgM阳性20例,阳性率为8.70%;多次妊娠者IgM阳性率(25.93%)明显高于初次妊娠者(6.40%)(χ2=11.43,P<0.05);IgM阳性孕妇的早期流产率为31.58%(6/19),而IgM阴性孕妇的早期流产率为8.53%(11/129),两者比较差异有统计学意义(P<0.05)。结论孕妇血清风疹病毒IgM抗体的测定有助于预测妊娠结局、降低先天性风疹综合征患儿的出现率。Objective To investigate the clinical value of detecting RV4gM antibody in sera of preg- nant women. Methods Enzyme-linked immunosorbent assay（ELISA） was used to detect RV-IgM specific an- tibody in sera of pregnant women. Results The positive rate of RV-IgM of the 230 pregnant women were 8.70% （20/230） ;The positive rate of RV-IgM in mnhigravida （25.93%） was markedly higher than primigravid women （ 6.40% ） （χ^2 = 11.43, P 〈 0. 05 ） ; The early abortion rate of IgM-positive pregnant women was 31.58% （6/19） , whereas IgM-negative pregnant women was 8.53% （ 11/129 ） （χ^2 = 8. 65, P 〈0. 05 ）. Conclusion the detection of RV-IgM specific antibody in sera of pregnant women will help to predict pregnancy outcome, and reduce the frequency of congenital rubella syndrome infant.

关 键 词：妊娠 风疹病毒 酶联免疫吸附试验 IGM 

分 类 号：R446.6[医药卫生—诊断学]