Experimental validation for time-domain fluorescence diffuse optical tomography of linear scheme  

作　　者：高峰 张丽敏 李娇 赵会娟 

机构地区：[1]College of Precision Instrument and Optoeletronics Engineering Tianjin University

出　　处：《Chinese Optics Letters》2008年第12期889-892,共4页中国光学快报（英文版）

基　　金：supported by the National Natural Science Foundation of China(No.60578008,60678049);the National Basic Research Program of China(No.2006CB705700);Tianjin Municipal Government of China(No.07JCYBJC06600)

摘　　要：We present a full three-dimensional, featured-data algorithm for time-domain fluorescence diffuse optical tomography that inverts the Laplace-transformed time-domain coupled diffusion equations and employs a pair of appropriate transform-factors to effectively separate the fluorescent yield and lifetime parameters. By use of a time-correlation single-photon counting system and the normalized Born formulation, we experimentally validate that the proposed scheme can achieve simultaneous reconstruction of the fluorescent yield and lifetime distributions with a reasonable accuracy.We present a full three-dimensional, featured-data algorithm for time-domain fluorescence diffuse optical tomography that inverts the Laplace-transformed time-domain coupled diffusion equations and employs a pair of appropriate transform-factors to effectively separate the fluorescent yield and lifetime parameters. By use of a time-correlation single-photon counting system and the normalized Born formulation, we experimentally validate that the proposed scheme can achieve simultaneous reconstruction of the fluorescent yield and lifetime distributions with a reasonable accuracy.

关 键 词：Diagnostic radiography Image segmentation Medical imaging Optical tomography Three dimensional Time domain analysis TOMOGRAPHY 

分 类 号：O439[机械工程—光学工程]