Measurement of crater geometries after laser ablation of bone tissue with optical coherence tomography  

作　　者：詹振林 张先增 叶青 谢树森 

机构地区：[1]Key Laboratory of Opto-Electronic Science and Technology for Medicine of Ministry of Education Fujian Normal University [2]Department of Otolaryngology Fujian Provincial Hospital,Fuzhou 350001 provincial Clinical College of Fujian Medical University

出　　处：《Chinese Optics Letters》2008年第12期896-898,共3页中国光学快报（英文版）

基　　金：supported by the National Natural Science Foundation of China(No.60578057);the Fujian Provincial Education Scientific Project(No.JA050217/JB06108)

摘　　要：The feasibility of measuring crater geometries by use of optical coherence tomography （OCT） is examined. Bovine shank bone on a motorized translation stage with a motion velocity of 3 mm/s is ablated with a pulsed CO2 laser in vitro. The laser pulse repetition rate is 60 Hz and the spot size on the tissue surface is 0.5 mm. Crater geometries are evaluated immediately by both OCT and histology methods after laser irradiation. The results reveal that OCT is capable of measuring crater geometries rapidly and noninvasively as compared to histology. There are good correlation and agreement between crater depth estimates obtained by two techniques, whereas there exists distinct difference between crater width estimates when the carbonization at the sides of craters is not removed.The feasibility of measuring crater geometries by use of optical coherence tomography （OCT） is examined. Bovine shank bone on a motorized translation stage with a motion velocity of 3 mm/s is ablated with a pulsed CO2 laser in vitro. The laser pulse repetition rate is 60 Hz and the spot size on the tissue surface is 0.5 mm. Crater geometries are evaluated immediately by both OCT and histology methods after laser irradiation. The results reveal that OCT is capable of measuring crater geometries rapidly and noninvasively as compared to histology. There are good correlation and agreement between crater depth estimates obtained by two techniques, whereas there exists distinct difference between crater width estimates when the carbonization at the sides of craters is not removed.

关 键 词：Ablation Biological radiation effects BONE Carbon dioxide CARBONIZATION Coherent light Diagnostic radiography Geometry HISTOLOGY Laser ablation Lasers Medical imaging Optical systems Optical tomography Tomography 

分 类 号：TN249[电子电信—物理电子学]