非高密度脂蛋白胆固醇在冠状动脉病变时的临床价值  

The clinical value of High-density Lipoprotein Cholesterol in the Corouary Artery Disease

作　　者：王凤清[1] 徐美华[1] 程祖建[1] 黄佳[1] 

机构地区：[1]福建医科大学附属第一医院检验科,福建福州350005

出　　处：《中国实验诊断学》2008年第12期1552-1554,共3页Chinese Journal of Laboratory Diagnosis

摘　　要：目的探讨非高密度脂蛋白胆固醇(non-HDL-C)与冠状动脉病变的关系。方法选取108例冠状动脉造影检查阳性的患者的血清,以健康体检者为对照,检测其总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)、载脂蛋白A1(ApoA1)、载脂蛋白B(ApoB),分析各血脂指标与冠心病的关系;并将冠心病组按病变程度分为单支病变组和双支病变组、3支及以上病变组,分析各指标与病变程度的关系。结果①与对照组相比,冠心病组TC、LDL-C、non-HDL-C显著增高。而HDL-C显著降低,P<0.05;②TC、non-HDL-C随病变支数的增多而增高,P<0.05。结论非高密度脂蛋白胆固醇在冠状动脉粥样硬化形成中具有重要的意义。Objective Explore non-high-density lipoprotein Cholesterol（non-HDL-c） Coronary Artery disedse.Methods Selected 108 cases of Coronary angiography in patients with serum positive, helthy subjects were used as controls. Detecction of total Cholesterol（TC） ,triglyceridcs（TG） ,low-density lipoprotein Cholesterol（LDL-C）, high-density lipoprotein Cholesterol（HDL-C） .Analysis of the relationship between serum lipid levels and coronary heart disease; CHD will be divided into groups according to degree of support single-vessel and double-vessel disease and more. Analysis of the lesions and blood lipid levels. Reesults ①Compared with the control group, total cholesterol coronary heart disease, LDL-C and TC increased significantly. HDL-C decreased significantly, P 〈 0.05. Conclusion non-high-density lipoprotein Cholesterol to coronary artery disease in the formation of major significance.

关 键 词：非高密度脂蛋白胆固醇 冠状动脉粥样硬化 

分 类 号：R541.4[医药卫生—心血管疾病]