同步辐射类同轴技术应用于肾脏成像的实验研究  

In vitro study of in-line holography with synchrotron radiation in kidney imaging

作　　者：彭屹峰[1] 陈绍亮[2] 陈岳声[1] 汤光宇[1] 赵文荣[1] 朱佩平[3] 黄万霞[3] 袁清习[3] 何伟[3] 

机构地区：[1]同济大学附属第十人民医院放射科,上海200072 [2]复旦大学附属中山医院核医学科,上海200032 [3]中国科学院高能物理研究所同步辐射装置实验室,北京100049

出　　处：《中国医学影像技术》2008年第11期1669-1671,共3页Chinese Journal of Medical Imaging Technology

基　　金：国家自然科学基金(30471652)

摘　　要：目的应用同步辐射光源的相干性,进行肾脏组织的类同轴成像研究,旨在评价相位衬度成像技术在软组织成像方面的意义。方法在北京同步辐射装置形貌站4W1A束线上,取经过4%甲醛溶液固定后的人体肾脏组织样品,置于类同轴光路的样品架上进行成像,以空间分辨率和组织衬度作为评价标准。结果在样品与成像板距离Z为150mm时获得的肾脏成像,具有较高的组织衬度,包括肾小囊在内的结构均能较好显示,通过显微放大法获得的空间分辨率达到30μm。结论类同轴技术能较好显示肾脏的微细解剖结构,对于以轻元素为主的脏器成像有较好的应用价值。Objective To assess the latent value of soft tissue imaging with phase contrast technology basing on the coherence character of synchrotron radiation （SR）. Methods Imaging of kidney was performed with in-line holography imaging technology. The experiments were performed in the 4W1A of the BSRF （Beijing synchrotron radiation facility in China）, the samples were soaked in 4% formalin solution, the samples were imaged on the shelf and in the ＂in-line＂ holography imaging setup. The spatial resolution and tissue contrast were served as evaluation element. Results When the distance was 150 mm between the sample and imaging plate, good contrast and high resolution were obtained in the ＂in-line＂ phase contrast imaging, the renal capsule revealed well, and the resolution reached to 30 micron. Conclusion The minute structure of kidney is well present with in-line holography imaging which is good for applying of main light element organization imaging.

关 键 词：同步辐射 相位衬度 类同轴成像技术 肾脏 

分 类 号：R543.3[医药卫生—心血管疾病] R-332[医药卫生—内科学]