δ-阿片受体激动剂DADLE对β-内啡肽和催乳素释放的影响  

Effects of DADLE, an Agonist for 6-Opiate Receptor,on β-Endorphin and Prolactin Release

作　　者：许荣焜[1] 全镭[1] 杨穗津[1] 黄醒亚[1] 

机构地区：[1]中国医学科学院基础医学研究所生理研究室

出　　处：《基础医学与临床》1990年第4期31-34,共4页Basic and Clinical Medicine

基　　金：国家自然科学基金

摘　　要：本工作给大鼠第三脑室微量注射δ-阿片受体相对选择性激动剂DADLE,增加血浆中β-内啡肽和催乳素的含量。结果表明,激活脑内δ-阿片受体,可同时兴奋上述垂体前叶激素的分泌。The effects of third ventricular injection(3rd V. I. )of (D-Ala2, D-Leu5) -enkephahn (DADLE) , a relatively selective agonist for 5-opiate receptor, on plasma concentration of β-endorphin (β-EP) and prolactin (PRL) were studied in conscious rats. The present results indicated that activation of δ-opiate receptor simultaneously stinulats β-enlorphin an 1 prolactin secretion.

关 键 词：垂体 Β-EP 催乳素 阿片受体 DADLE 

分 类 号：R335.1[医药卫生—人体生理学]