前列腺疾病MRS检查鉴别诊断标准的制定方法  

Study on the diagnostic criteria of benign prostatic hyperplasia in MRS

作　　者：史志杰[1] 李峰[2] 曹凤宏[2] 王守红[2] 王霄英[3] 赵丽君[4] 李晓强[2] 

机构地区：[1]唐山工人医院分院泌尿外科,河北唐山063000 [2]华北煤炭医学院附属医院泌尿外科,河北唐山063000 [3]北京大学第一医院医学影像科,北京100034 [4]华北煤炭医学院附属开滦医院核磁共振室,河北唐山063000

出　　处：《西部医学》2009年第1期51-53,共3页Medical Journal of West China

基　　金：河北省科学技术研究与第二批指导计划项目(No.062761996)

摘　　要：目的探讨适合中国人前列腺疾病鉴别诊断标准的制定方法。方法对16例前列腺增生的患者术前行MRS检查,观察枸橼酸盐(Cit)胆碱化合物(Cho)和肌酸(Cre)波峰,并测定不同单体的(Cho+Cre)/Cit值(包括尿道周围单体)。耻骨上经膀胱前列腺摘除术后前列腺标本进行大病理切片检查,将波谱图像的(Cho+Cre)/Cit值与前列腺的病理类型分别进行记录。结果仅腺体增生型与尿道周围单体相近,其余任意两组间比较均不同。结论前列腺大病理切片检查技术对应MRS检查的波谱图像是制定适合中国人前列腺疾病鉴别诊断标准的可行性的方法。Objective To study the methods of the diagnostic criteria of benign prostatic hyperplasia with MRS. Methotis The appearances of magnetic resonance spectroscopy in sixteen patients with benign prostatic hyperplasia were analyzed. The peaks of citrate, choline and creatine were observed. The ratios of choline ＋ creatine and citrate were measured. After suprapubic transvesical prostatectomy, the specimens were inspected with pathologic section. The values of cho ＋ cre/cit and pathologic types of benign prostatic hyperplasia were recorded. Results The ratios of choline ＋ creatine and citrate of three pathologic types of benign prostatic hyperplasia, including gland hyperplasia, matrix hyperplasia and mixing hyperplasia, were 0. 59 ± 0. 29, 1.23 ± 0. 38, and 0. 80 ± 0. 27, respectively, which were statistically different from each other （ P 〈 0. 05 ）. Conclusion MRS combined with pathologic sections of prostate was a feasible method to determine the diagnostic criteria of benign prostatic hyperplasia in china.

关 键 词：良性前列腺增生 磁共振波谱分析 病理类型 诊断标准 

分 类 号：R697.3[医药卫生—泌尿科学]